Tag: biomarker

A systematic review in Diagnostic Pathology evaluates Cytokeratin 19 expression across 476 human malignant cell lines, highlighting its role in ...

An exploratory study of 67 systemic sclerosis patients found that machine learning models built from HRCT radiomic features detected interstitial ...

A new prognostic model for hepatocellular carcinoma identifies ANGPT2 as a key driver of malignant progression and immune resistance.

A five-gene blood panel built from neutrophil-driven transcriptomic signatures classified severe acute pancreatitis with an AUC of 0.890 against milder ...

A single-centre cohort study in Egypt identifies urinary soluble CD163 as a biomarker strongly associated with active lupus nephritis and ...

A retrospective study of 233 patients with advanced hepatocellular carcinoma in Vietnam found that a pretreatment neutrophil-to-lymphocyte ratio of 3.6 ...

A multicenter study links elevated soluble PD-1 to lupus nephritis severity and shows that neutralizing it improves kidney outcomes in ...

Regional brain ferritin accumulation tracks pathological TDP-43 signatures across aging, Alzheimer's disease, and amyotrophic lateral sclerosis.

A systematic review and meta-analysis found significantly higher circulating lipocalin-2 levels in patients with metabolic dysfunction-associated steatotic liver disease compared ...

Changes in three-dimensional choroidal luminal volume measured four months after starting low-dose atropine predicted two-year treatment response in 290 myopic ...

Researchers at the University of Gothenburg in Sweden have outlined a protocol for the BARITONE project, a study designed to ...

A new study links sperm PLCZ1 mRNA levels to embryo quality in ART, suggesting a dual role for PLCZ1 in ...

A study in BMC Immunology identifies serum miR-181a-2-3p as a diagnostic biomarker for sepsis with predictive value for clinical outcomes.

A retrospective study of 102 elderly patients found that the triglyceride–glucose index is significantly elevated in vascular cognitive impairment and ...

A study in BMC Immunology identifies serum SDF4 as a potential biomarker for diagnosing systemic lupus erythematosus and assessing disease ...

Spatial profiling of melanoma tumors reveals that lipid-associated macrophage neighborhoods drive immune exclusion and predict resistance to checkpoint inhibitor therapy.

An integrative bioinformatics study with experimental validation identifies PRICKLE1 as a potential hub gene and biomarker in keloids.

A new review argues that acetylcholinesterase acts beyond breaking down acetylcholine, accelerating amyloid-beta aggregation and tau pathology while remaining a ...

Researchers report that stromal APOL4 marks a distinct cancer-associated fibroblast state whose loss confers carboplatin resistance in ovarian cancer co-cultures ...

A computational study from the University of Kalyani predicts the structural features of Aβ175, a protein encoded by the circular ...