Chest CT Scans Could Secretly Reveal Your Heart Attack Risk Years Early
Researchers show that routine chest CT scans, combined with machine learning analysis of body composition and clinical data, can opportunistically ...
Tag: Atherosclerosis
Maternal high-fat diet before pregnancy may program offspring heart disease risk
A new review synthesizes evidence that maternal high-fat diet before and during pregnancy may program offspring coronary artery disease risk ...
Prior Stroke Leaves a Hidden Signature in the Coronary Arteries, OCT Study Reveals
Optical coherence tomography imaging of 386 matched heart attack patients shows that those with a prior ischemic stroke carry more ...
PFOS Exposure May Trigger Early Atherosclerosis, Zebrafish Study Reveals
A new study has revealed that exposure to perfluorooctane sulfonate, better known as PFOS, may trigger the earliest phenotypic alterations ...
Innate Immune Memory: How Epigenetic and Metabolic Rewiring Shapes Health and Disease
A new review in the Journal of Molecular Medicine explains how trained immunity, driven by epigenetic and metabolic reprogramming of ...
Adropin: The Metabolic Hormone Rewiring the Map of Chronic Disease
A new review maps how the peptide hormone adropin, once seen as a simple metabolic signal, orchestrates vascular, neurological, fibrotic, ...
How Plant Polyphenols May Slow the Arterial Damage Behind Heart Attacks and Stroke
A new review in Molecular Biology Reports maps how dietary polyphenols such as resveratrol, quercetin, catechins, curcumin and anthocyanins target ...
Fat Around the Heart Grows Larger and Denser in Psoriasis, CT Study Finds
A propensity score-matched CT study found that adults with psoriasis have larger and denser epicardial adipose tissue than matched controls, ...
Vascular Receptor TLR4 Emerges as a Master Switch Between Vascular Aging and Targeted Senotherapeutics
A new review in Aging Cell positions endothelial TLR4 as a context-dependent molecular rheostat controlling vascular senescence, arguing that precision ...
The Dark Side of Good Cholesterol: Rogue HDL Particle Drives Arterial Aging
Scientists have identified an electronegative HDL subfraction enriched in apolipoprotein(a) that induces endothelial senescence through the p53–p21 pathway and accelerates ...
Immune Antibodies Linked to Stroke Recovery and Relapse Risk in Landmark Berlin Study
A prospective Berlin study of 562 ischemic stroke patients finds that both high and low levels of autoantibodies targeting G ...
Overactive Inflammasome in Artery Muscle Cells Drives Dangerous Vessel Thickening in Mice
A new mouse study shows that hyperactive NLRP3 inflammasome signaling within vascular smooth muscle cells drives inflammation, pyroptosis, lipid accumulation, ...
3D Printed Polymers Mimic Atherosclerotic Blood Vessels’ Properties
Researchers have continually pushed the boundaries of medical technology, particularly when it comes to simulating human tissues for training and ...
How Aging and Shear Stress Affect Vascular Health
Aging is an inevitable biological process that profoundly affects various physiological systems and increases vulnerability to diseases, particularly cardiovascular diseases. ...
CNIC scientists discover a new cardiovascular risk factor and identify a drug able to reduce its effects
To the known risk factors for cardiovascular disease—high blood pressure, high cholesterol, diabetes, overweight and obesity, smoking, and physical inactivity—a ...
