Most Penicillin Allergy Labels Are Wrong, and Doctors Are Finally Removing Them
A new narrative review argues that most of the roughly 10% of patients labeled penicillin-allergic are not truly allergic, and ...
Tag: antibiotic resistance
Scientists uncover hidden weakness in antibiotic-resistant bacteria
A Umeå University study shows that disrupting the cell wall transport lipid undecaprenyl phosphate blocks evolutionary escape routes in MRSA ...
New Indole-Fused Molecules Show Potent Antibacterial Power Against Resistant Superbugs
A newly synthesized family of indole-fused oxazepine compounds shows potent, broad-spectrum antibacterial activity and favorable predicted safety, with one derivative ...
Ragweed Pollen Can Trigger Antibiotic-Resistant Staph Pneumonia, Mouse Study Shows
A new mouse study suggests ragweed pollen can carry antibiotic-resistant MRSA deep into the lungs, worsening pneumonia and weakening the ...
Novel Anaprazole-Based Quadruple Therapy Matches Rabeprazole in H. pylori Eradication Trial
A randomized controlled trial in Jiangsu Province found that anaprazole-based bismuth quadruple therapy is non-inferior to the rabeprazole-based standard for ...
Fungus Hidden in a Medicinal Plant Yields a Potent New Weapon Against MRSA
An endophytic fungus from Vinca minor produces a decalin-containing tetramic acid that potently kills MRSA in laboratory tests, though its ...
Gentamicin’s Hidden Impurities May Drive Toxicity, Landmark Antibiotic Comparison Finds
A comprehensive head-to-head comparison of 26 aminoglycoside antibiotics reveals that two overlooked gentamicin impurities, B1 and X2, are far more ...
Vegan honey engineered to match mānuka’s bacteria-killing power
Aston University researchers have engineered vegan honey formulations containing methylglyoxal and hydrogen peroxide-generating systems that can kill the drug-resistant bacterium ...
Persister Cells May Explain Why Urinary Tract Infections Keep Coming Back
A new Perspective in Nature Reviews Urology argues that antibiotic tolerance and persister cells, rather than resistance alone, may explain ...
Carbon Dots and Titanium Dioxide Turn Polymer Membranes into Antibiotic-Destroying Water Filters
Researchers in India have developed an electrospun PVDF membrane loaded with carbon quantum dots and titanium dioxide that removes 74.4 ...
Cell-Mimicking Nanoparticles Earn UC San Diego Engineer MacArthur Genius Grant
UC San Diego nanoengineer Liangfang Zhang has won a 2026 MacArthur Fellowship for his pioneering cell-mimicking nanoparticles that camouflage drugs, ...
Childhood UTI Bacteria Show Soaring Ciprofloxacin Resistance in Six-Year Hospital Study
A six-year analysis of over 10,000 pediatric urine isolates at a Turkish tertiary hospital finds ciprofloxacin resistance in E. coli ...
Machine Learning Predicts Antibacterial Drug Synergy Without Data Leakage
Researchers developed HALO, a machine-learning framework that predicts antibacterial drug synergy from multi-level bioactivity features while exposing how data leakage ...
Flexible Tail on Listeria Chaperone Protein Proves Key to Virulence and Antibiotic Resistance
A short serine-rich disordered tail on the Listeria monocytogenes chaperone PrsA2 proves essential for folding the toxin listeriolysin O, driving ...
Spring Water Linked to Tularemia Cluster in Rural Türkiye
A cluster of 13 tularemia cases in Manisa, Türkiye, has been linked to contaminated natural spring water, with most patients ...
Cryo-EM Reveals How Bacteria Switch On Their Lipopolysaccharide Transport Machine
Cryo-electron microscopy structures of the complete Lpt bridge show that a single transmembrane helix of LptC acts as a substrate-responsive ...
Cell Division Switch in Pseudomonas Reveals New Route to Antibiotic Resistance
Mutations in the pedestal domain of the cell division protein FtsI alter how Pseudomonas aeruginosa regulates septal cell wall synthesis ...
Scientists Find Active Pseudomonas Phages and Their Bacterial Host in Human Breast Milk
Researchers have isolated six infectious Pseudomonas aeruginosa bacteriophages, along with a live strain of the bacterium itself, directly from human ...
Natural Alkaloids Show Promise as Disruptors of Bacterial Quorum Sensing
A computational study finds that the natural alkaloids lanoginosine and liriodenine bind strongly and stably to the AgrA LytTR domain ...
Virtual screen of 12 million compounds yields new bacterial kinase inhibitors
Japanese researchers used an amino acid mapping descriptor derived from the natural antibiotic waldiomycin to screen nearly 12 million compounds ...
