A scientific review examines how modulating the fibroblast growth factor system could provide therapeutic strategies for Alzheimer's disease by intervening ...
A critical review reveals how bidirectional disruptions between tau protein and neuronal microtubules may accelerate Alzheimer disease, exposing critical biomarker ...
A medical case report reveals that comorbid early-onset Alzheimer’s disease can mimic cognitive progression independent of relapse activity in a ...
A sequential plasma testing strategy using p-tau217 followed by the p-tau217/Aβ42 ratio reduced diagnostic indeterminacy to 12.3 percent in a ...
A scientific review positions fibroblast growth factor signalling as an underexplored neuropharmacological axis for developing disease-modifying therapies in Alzheimer's disease.
A new study in European Radiology Experimental shows that quantitative T1 mapping on MRI correlates with amyloid burden in Alzheimer’s ...
A systematic review and meta-analysis found that individuals with type 2 diabetes had an increased risk of Alzheimer's disease alongside ...
A multi-cohort study of donor brain tissue shows that molecular sex differences in the Alzheimer's cortex represent stable offsets that ...
Researchers have identified a significant statistical association between levels of glucagon-like peptide-1 receptor (GLP-1R) in cerebrospinal fluid and tau pathology ...
The study, published in Discover Pharmaceutical Sciences, demonstrates that encapsulating RHT in polycaprolactone microspheres and coating them with transferrin significantly ...
Polysomnography reveals progressive slow-wave sleep deterioration across the Alzheimer’s disease continuum, with slow-wave morphology predicting longitudinal cognitive trajectories in preclinical ...
Researchers have identified a distinct molecular signature in blood that can separate Alzheimer's disease from amyotrophic lateral sclerosis, two neurodegenerative ...
A systematic review and meta-analysis published in the European Review of Aging and Physical Activity reports that physical exercise is ...
A single-cell transcriptomic study in mice reveals how periodontal inflammation exacerbates neuroinflammatory signaling and alters glial cholesterol pathways in early ...
A retrospective single-center cohort study published in Alzheimer's Research & Therapy reports that approximately half of patients with early Alzheimer’s ...
A systematic review details how combining cerebrospinal fluid, blood, and saliva biomarkers establishes an accessible biological framework for diagnosing and ...
A narrative review indicates that blood-brain barrier disruption in Alzheimer's disease increases cerebral antipsychotic penetration, triggering parkinsonian side effects and ...
A retrospective study of 63 patients found that amyloid and tau biomarker groups differed in baseline cognition, psychiatric symptoms and ...
A bidirectional AI model combining speech acoustics with transcript meaning reached 90.42% accuracy on the ADReSS Alzheimer’s disease benchmark in ...
A study of nearly 6,000 people shows the APOE ε4 variant steepens age-related shifts in plasma biomarkers of Alzheimer's disease, ...
