Scientists Watch RNA-Binding Proteins Assemble on Nascent Transcripts in Real Time
Fluorescent tagging in living cells reveals the ordered recruitment of RNA-binding proteins to nascent intronless transcripts, including a temporal gap ...
Tag: ALYREF
RNA Chaperone ALYREF Hijacks Poly-ADP-Ribose at DNA Breaks and Slows Repair in Tumor Cells
Researchers report that the RNA-processing protein ALYREF binds poly-ADP-ribose at DNA double-strand breaks, delaying repair when overexpressed and marking a ...
TRPM7 Channel Drives Heart Damage After Ischemia-Reperfusion Through a Newly Traced Molecular Pathway
A new study in mice and cardiomyocytes shows that TRPM7 promotes ischemia-reperfusion heart injury through a CaMKII/DDX3X/NLRP3 pathway that drives ...
