• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • CONTACT US
Wednesday, March 29, 2023
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • CONTACT US
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • CONTACT US
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News

SUTD researchers developed DIY 3D-printed peristaltic pump kits for microfluidics

Bioengineer by Bioengineer
December 20, 2021
in Science News
Reading Time: 3 mins read
0
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

The development of microfluidic systems for lab-on-a-chip (LoC) and organs-on-a-chip (OoC) applications require precise fluid flow control. Typically, on-chip flows are controlled by integrating a microfluidic chip with external pumps that deliver fluid flow at the microscale (typically on the order of mL/min) through the microchannels. To this end, commercially available flow devices such as extrusion syringe pumps, peristaltic pumps and pneumatic pumps have been widely used.

Image of the 3D-printed peristaltic pump kit.

Credit: SUTD

The development of microfluidic systems for lab-on-a-chip (LoC) and organs-on-a-chip (OoC) applications require precise fluid flow control. Typically, on-chip flows are controlled by integrating a microfluidic chip with external pumps that deliver fluid flow at the microscale (typically on the order of mL/min) through the microchannels. To this end, commercially available flow devices such as extrusion syringe pumps, peristaltic pumps and pneumatic pumps have been widely used.

Unfortunately, existing pumps suitable for microfluidic applications are usually bulky and costly. For example, pressure-controlled flow systems cost as much as US$10,000, whereas syringe pumps and peristaltic pumps cost hundreds to thousands of dollars. Pumps with a small footprint are preferred for LoC and OoC applications. While miniature pumps are commercially available, they require proprietary and expensive control systems (over US$1000). More importantly, these commercially available pumps are not amenable to customisation. Since each experiment has unique requirements such as flowrate, working environment, and available space, rapid customisation of the instrument would benefit users.

To make microfluidic pumps more accessible to the scientific community, researchers from the Singapore University of Technology and Design (SUTD) Soft Fluidics Lab developed a “highly-customisable, 3D-printed peristaltic pump kit”, where users from around the world can download the design files, 3D-print and assemble their do-it-yourself (DIY) peristaltic pump (refer to image).

“3D printers have become more and more affordable, and they are a commodity that is found in most scientific laboratories today. With the advancement of 3D printing technologies, scientists no longer have to rely on manufacturers to manufacture components; they can design and print them themselves at an affordable cost. We are slowly observing the democratisation of manufacturing by 3D printing technology,” said Associate Professor Michinao Hashimoto, the project’s principal investigator from SUTD.

The peristaltic pump is powered and controlled by Arduino, an open-source electronics platform. “With the introduction of Arduino, precise control of motors is becoming accessible to non-experts. These open-source electronic platforms are empowering scientists with little background in electronics and programming to build complex scientific instrumentations,” explained lead author Terry Ching, a joint graduate student with SUTD and National University of Singapore (NUS).

By combining 3D-printed parts with open-source electronic prototyping platforms, the team built a peristaltic pump comparable to commercially available options at a fraction of the cost, an estimated US$50 per pump. The assembled pumps offered a wide range of flowrate for microfluidic users (0.02 – 727.3 μL/min). The pump also has a small footprint of around 20 × 50 × 28 mm, which can be placed in a cell incubator. Notably, the pump is designed in the form of a kit, allowing end-users to customise the setup according to their preference.

“We believe that a kit has the intrinsic ability to evoke the culture of hacking and tinkering. Hopefully, this can in turn inspire the scientific community to develop more open-source scientific infrastructure,” added Professor Hashimoto.

Computer-aided design (CAD) files with detailed instructions to fabricate the pump is found in their latest publication, “Highly-customisable 3D-printed peristaltic pump kit” in HardwareX. This research was conducted in collaboration with the research groups of Professor Yi-Chin Toh (Queensland University of Technology), Associate Professor Javier Fernandez (SUTD) and Professor Chwee Teck Lim (National University of Singapore).



Journal

HardwareX

DOI

10.1016/j.ohx.2021.e00202

Article Title

Highly-customizable 3D-printed peristaltic pump kit

Article Publication Date

19-Nov-2021

Share12Tweet8Share2ShareShareShare2

Related Posts

Figure 1

Revolutionary battery technology to boost EV range 10-fold or more

March 29, 2023
Cubane molecule

‘Chemical cube’ tools for building new drugs and agrochemicals

March 29, 2023

Detecting coral biodiversity in seawater samples

March 29, 2023

Light-bending gravity reveals one of the biggest black holes ever found

March 29, 2023

POPULAR NEWS

  • ChatPandaGPT

    Insilico Medicine brings AI-powered “ChatPandaGPT” to its target discovery platform

    66 shares
    Share 26 Tweet 17
  • Northern and southern resident orcas hunt differently, which may help explain the decline of southern orcas

    44 shares
    Share 18 Tweet 11
  • Skipping breakfast may compromise the immune system

    43 shares
    Share 17 Tweet 11
  • Insular dwarfs and giants more likely to go extinct

    35 shares
    Share 14 Tweet 9

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

Revolutionary battery technology to boost EV range 10-fold or more

‘Chemical cube’ tools for building new drugs and agrochemicals

Detecting coral biodiversity in seawater samples

Subscribe to Blog via Email

Enter your email address to subscribe to this blog and receive notifications of new posts by email.

Join 48 other subscribers
  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In