Cancer Cells Rewire Their Fuel Supply When This Growth Signal Switches On
One of the most stubborn killers in oncology is quietly being re-understood at the level of its molecular plumbing. Head ...
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From Code Status to Real Conversation: How Doctors Actually Learn to Talk About Goals of Care
Few moments in medicine carry more weight than a conversation about goals of care. When a patient faces a serious, ...
CRISPR and Nanopore Sequencing Reveal Hidden RNA Tags in E. coli
Inside every bacterial cell, RNA molecules carry far more information than their sequence of bases alone. After transcription, the four ...
Tantalum-doped nanorod catalyst doubles as anti-allergy drug discovery platform
Chemists at the University of Kashan have unveiled a multifunctional nanomaterial that works equally hard as a green synthetic catalyst ...
Prime Assembly Enables Targeted Genomic Integration and Large-Scale DNA Rearrangements
A new genome-editing strategy described in Nature promises to push DNA writing far beyond the limits of existing tools. The ...
Heterogeneous Graphs Help AI Crack Geometry Problems
Solving a plane geometry problem is deceptively hard for a machine. A human student glances at a diagram, reads a ...
AI-Powered Imaging Spots Skin Cancer Before It Becomes Visible
Basal cell carcinoma is the most common form of skin cancer worldwide, and for most patients it is highly treatable ...
Tiny Biosensors Could Detect Alzheimer’s and Parkinson’s Years Before Symptoms
Neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, and prion disorders are among the most formidable challenges in modern medicine, ...
Sandy Secrets Beneath Brazil’s Cerrado: New Study Rewrites the Story of Tropical Ferralsols
Deep beneath the soybean fields now spreading across the Brazilian state of Piauí lies a soil whose story has long ...
Scientists Watch Single Platinum Atoms Rearrange During Catalysis, Revealing Two Kinds of Active Sites at Once
For nearly a century, chemists have puzzled over the exact location on a catalyst’s surface where molecules transform. Now a ...
Open-Source Machine Learning Workflow Accelerates Discovery of Small-Molecule PD-L1 Cancer Inhibitors
Immunotherapy has transformed the treatment of many cancers, and few targets have proven as consequential as the interaction between the ...
Voice-Controlled AI Agent Lets Quadruped Robot Understand English and Slovak Commands
A century ago, the Czech writer Karel Čapek gave the world the word “robot” in his play R.U.R., imagining artificial ...
Plant Compound Bellidifolin Shields Livers From Chemotherapy Damage
Doxorubicin is one of the most effective and most widely used chemotherapy drugs in the world, deployed against breast cancer, ...
Rare Bladder Metastasis From Kidney Cancer Emerges After Targeted Therapy Fails
A fifty-year-old woman walked into a hospital for what should have been a routine check-up, carrying no symptoms at all. ...
Decades-Old Newborn Blood Spots Yield High-Quality DNA Methylation Data With Tiny DNA Inputs
Deep in a refrigerated repository in Sweden lies one of the most remarkable biomedical archives in the world: the Phenylketonuria ...
Cleaner Air Slows Kidney Disease Progression in Half-Million-Patient Taiwan Study
For the millions of people living with early-stage chronic kidney disease, the countdown to dialysis is one of medicine’s most ...
Rare Hip Tumor Masquerading as Infection Diagnosed Through Imaging and Pathology
A 56-year-old man who walked into a hospital with four days of severe right hip pain, weeks after a frightening ...
Chemists Thread Eight Molecular Helices Into Single Nanographenes
Researchers have unveiled a modular stereoselective synthetic strategy that allows them to control, with unprecedented precision, the handedness of multiple ...
ICU Care for Acute Leukemia Is No Longer a Death Sentence, Landmark Analysis Shows
For decades, the words intensive care and acute leukemia were spoken together with a sense of resignation. Patients with newly ...
CRISPRi Screens Inside Living Mice Map How E. coli Adapts to the Gut
Escherichia coli is one of the most genetically versatile bacteria known to science, capable of living as a harmless gut ...