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Home NEWS Science News Health

Research Reveals Reduced Disparity in Heart Disease Outcomes Between Men and Women Over Two Decades

Bioengineer by Bioengineer
March 31, 2025
in Health
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Women and Heart Photo

Heart disease is often misperceived as primarily a man’s issue, leading to a dangerous underestimation of its impact on women. The prevailing image—of a man clutching his chest during a heart attack—fails to capture the reality that heart disease remains the leading cause of death among women in the United States. Recent research conducted by heart experts at Intermountain Health in Salt Lake City illuminates this critical issue, revealing significant disparities in risk factors, presentation, and outcomes between male and female patients suffering from cardiac conditions.

The alarming statistics indicate that nearly 45% of women over the age of 20 in the United States live with cardiovascular disease, a number that underscores the urgency of addressing heart health in females. This study highlights the narrowing gap in mortality and cardiac events between men and women, an indicator of both progress and ongoing challenges in cardiovascular care. As the principal investigator, Kismet Rasmusson, NP, articulates, the distinct biological and physiological characteristics that differentiate women from men necessitate tailored diagnostic and therapeutic approaches to effectively combat heart disease.

Throughout a comprehensive retrospective analysis, researchers meticulously reviewed the electronic health records of 14,248 women and 26,524 men who underwent coronary angiography between 2000 and 2019 at Intermountain facilities. This medical imaging technique employs X-rays and contrast dye to visualize coronary arteries, playing a critical role in identifying blockages that could precipitate heart attacks. The study not only uncovers the gender-specific nuances in heart disease but also showcases the complexities of its presentation in women, who are often older and present with different comorbidities compared to their male counterparts.

Researchers noted that men exhibited higher rates of traditional risk factors such as smoking, previous heart attacks, and left ventricular dysfunction. Meanwhile, women tended to have a higher prevalence of conditions such as hypertension and diabetes. They often presented with stable angina yet experienced less severe acute symptoms at the time of catheterization. This finding raises critical questions regarding how cardiovascular health providers perceive and manage female patients with heart disease, potentially underscoring an implicit bias that may endanger their health.

Furthermore, a significant finding from the study revealed that even when women were diagnosed with serious arterial blockages, they were prescribed fewer life-saving cardiac medications compared to men. This discrepancy in treatment raises alarm bells about gender-based disparities in medical care, questioning whether female patients are receiving adequate therapeutic interventions corresponding to their needs and risk profiles.

Throughout the 19-year study, the discrepancies in major cardiac events—like heart attacks and mortality—favored men, a trend largely driven by the higher death rates in women. However, the data presented by the researchers indicated an encouraging trend; when analyzed over five-year increments, the significant differences between genders in major cardiac events began to diminish, demonstrating improvement in cardiac care approaches toward women as the years progressed.

The alarming decline in women’s awareness of their heart disease risk poses another significant challenge. Research indicates that awareness levels have drastically dropped; from 65% in 2009 to a mere 44% by 2019. This awareness is pivotal, as recognizing risk factors can dramatically affect outcomes. A similar pattern was observed in a 2021 publication in the journal Circulation, where less than half of women demonstrated an understanding of their risks for developing cardiovascular disease.

The ramifications of these findings underscore the urgency of increasing educational initiatives aimed at improving female heart health awareness. Rasmusson emphasizes the paramount importance of women understanding that their risk of heart disease is as substantial as men’s, emphasizing that it surpasses the combined mortality rates of all cancers. Prompt recognition of symptoms and effective management of risk factors are critical attributes women must embrace to positively influence their cardiovascular health outcomes.

As heart health researchers continue to advocate for a broader, more inclusive approach to cardiovascular medicine—one that emphasizes the unique characteristics of female patients—there emerges a collective call to action. National leaders in women’s cardiovascular health stress the urgency of further research into understanding how heart disease affects women differently from men. This ongoing inquiry into gender-specific risk factors, symptoms, and treatment approaches will be critical in closing the existing gaps in care.

While this study offers vital insights, it is essential to note its limitations. Conducted within a single healthcare system, its findings may not reflect national trends universally. Yet, the implications of this research extend far beyond these confines, as they highlight the broader systemic issues of under-representation of women in cardiovascular research and the tendency for medical literature to default to male-centered studies.

The study’s conclusions were presented at the American College of Cardiology’s annual scientific session, aiming to spark discussions about how to effectively bridge these gaps in care and enhance our understanding of women’s heart health. As we move forward, addressing these disparities will not only improve health outcomes for women but will also foster a more inclusive medical community, where every patient’s unique health needs are acknowledged and addressed.

Recognizing that heart disease is a complex interplay of genetics, lifestyle, and environmental factors, it becomes imperative for both patients and healthcare providers to engage in comprehensive dialogue about risk factors. Women should be encouraged to actively participate in their health management, ensuring they seek prompt medical attention when symptoms arise and empowering them to advocate for their care.

In conclusion, a paradigm shift is essential in the realm of cardiovascular health to better align care practices with the unique characteristics that define female heart disease. Empowering women with knowledge, fostering greater awareness, and prioritizing research will ultimately lead to more effective and equitable cardiovascular care, which can save lives and transform the landscape of heart health for future generations.

Subject of Research: Observational study on gender differences in heart disease outcomes
Article Title: Women and Heart Disease: Closing the Gap in Care
News Publication Date: March 31, 2023
Web References: Intermountain Health
References: Circulation, American College of Cardiology Studies
Image Credits: Credit: Intermountain Health

Keywords: Women’s cardiovascular health, heart disease, coronary angiography, health disparities, awareness of heart disease risks.

Tags: addressing women’s heart healthcoronary angiography research findingsdisparities in cardiovascular healthgender differences in cardiovascular diseaseheart disease outcomes by genderheart health awareness for womenIntermountain Health heart disease studymortality rates in heart diseaseprogress in cardiac care for womentailored treatments for female heart patientsunderstanding heart disease in womenwomen and heart disease statistics

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