• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
Tuesday, August 26, 2025
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Health

Poo transplant effective treatment for chronic bowel condition

Bioengineer by Bioengineer
January 15, 2019
in Health
Reading Time: 2 mins read
0
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

Poo transplant or “Faecal microbiota transplantation” (FMT) can successfully treat patients with ulcerative colitis, new research from the University of Adelaide shows.

The randomised, double-blind study – published in the journal JAMA – was a collaboration between the University of Adelaide, South Australian Health and Medical Research Institute (SAHMRI), CSIRO and CALHN (SA Health).

It involved 73 adults with mild to moderate active ulcerative colitis, an inflammatory bowel disease which effects the lining of the large intestine and rectum causing symptoms including pain, bloody stools and an increased risk of colon cancer.

Patients received either pooled donor FMT that had been anaerobically processed or their own stool as placebo via colonoscopy followed by two enemas.

Researchers found a short duration of low intensity FMT using anaerobically (in an oxygen-free environment) prepared pooled donor FMT could induce remission in ulcerative colitis, with a 32% rate of remission compared to 9% with placebo. This is a similar treatment result to the best currently available therapies.

Many of the currently available therapies for ulcerative colitis improve the disease by suppressing the immune system which can lead to potential side effects like infection or malignancy.

“The most important difference in this trial compared to previous studies is the use of anaerobic (oxygen-free) stool processing,” says study leader Dr Sam Costello, Gastroentrologist, The Queen Elizabeth Hospital and Lecturer, University of Adelaide’s Medical School.

“Many gut bacteria die with exposure to oxygen and we know that with anaerobic stool processing a large number of donor bacteria survive so that they can be administered to the patient.

“We believe that this may be the reason that we had a good therapeutic effect with only a small number of treatments.”

An agreement has already been reached with UK company Microbiotica to commercialise the development of a microbial therapeutic from the study.

“Our long-term aim is to develop rationally designed microbial therapies that can replace FMT,” says Dr Costello.

“These will have bacteria in a pill that can carry out the therapeutic effect without the need to take whole faeces.

“This is obviously a better and less smelly option.”

Further studies will investigate whether FMT can maintain remission in ulcerative colitis.

###

Media Contact
Sam Costello
[email protected]
61-041-331-1793

Related Journal Article

http://doi.org/10.1001/jama.2018.20046
http://dx.doi.org/10.1001/jama.2018.20046

Tags: Internal MedicineMedicine/Health
Share12Tweet8Share2ShareShareShare2

Related Posts

Targeted Prostate Screening: Reducing Harm through Age Stratification

August 26, 2025

Aortic Valve Guides Umbilical Artery Catheter Placement

August 26, 2025

Improved Stroke Outcomes for Older Patients in Collaborative Care

August 26, 2025

Identifying Late-Onset Sepsis Markers in Pediatric ICU

August 26, 2025
Please login to join discussion

POPULAR NEWS

  • blank

    Breakthrough in Computer Hardware Advances Solves Complex Optimization Challenges

    146 shares
    Share 58 Tweet 37
  • Molecules in Focus: Capturing the Timeless Dance of Particles

    142 shares
    Share 57 Tweet 36
  • New Drug Formulation Transforms Intravenous Treatments into Rapid Injections

    115 shares
    Share 46 Tweet 29
  • Neuropsychiatric Risks Linked to COVID-19 Revealed

    81 shares
    Share 32 Tweet 20

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

JUNO Successfully Completes Liquid Filling and Commences Data Acquisition

Targeted Prostate Screening: Reducing Harm through Age Stratification

Aortic Valve Guides Umbilical Artery Catheter Placement

  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.