• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
Thursday, October 9, 2025
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Biology

Pennington Biomedical researcher Dr. Carrie Elks awarded $1.4 million to study fat cell communication cycle

by
August 6, 2024
in Biology
Reading Time: 3 mins read
0
Dr. Carrie Elks
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

​The National Institutes of Health’s National Institute of Diabetes and Digestive and Kidney Diseases, or NIDDK, awarded Pennington Biomedical researcher Dr. Carrie Elks a grant of $1.4 million to explore insulin resistance and inflammation in fat cells. Dr. Elks will apply the grant toward her Matrix Biology Laboratory’s project “Adipocyte cytokine signaling as a coordinator of adipose tissue function.” 

Dr. Carrie Elks

Credit: Pennington Biomedical Research Center

​The National Institutes of Health’s National Institute of Diabetes and Digestive and Kidney Diseases, or NIDDK, awarded Pennington Biomedical researcher Dr. Carrie Elks a grant of $1.4 million to explore insulin resistance and inflammation in fat cells. Dr. Elks will apply the grant toward her Matrix Biology Laboratory’s project “Adipocyte cytokine signaling as a coordinator of adipose tissue function.” 

The proposed project is based on a communication loop that was recently discovered by Dr. Elks and her team. The bidirectional communication loop is between fat cells and immune cells. Interruptions to this loop promote obesity and reduces function of fat tissues. The loop is governed by a small protein called Oncostatin M, or OSM, and the project will further explore how the protein and its communication loop operate in maintaining body weight. 

“I’m grateful that the NIDDK has evaluated this discovery and our planned research to be worthy of this generous grant,” said Dr. Elks, assistant professor-research at Pennington Biomedical Research Center and LSU alumna. “The communication between fat cells and immune cells is crucial for fat tissues to work properly, and the ways in which fat cells respond to immune cells can change, resulting in inflammation. The results of this study will ideally reveal new patterns in cell communication that can be further evaluated to treat obesity and other metabolic diseases.” 

The OSM protein is produced by immune cells in fatty tissue, but the lab’s research shows that when fat cells lack the receptor for OSM, this leads to fat tissue inflammation and insulin resistance. The lab’s findings suggest that signals from the OSM protein are needed for fat tissues to function properly, but how such an interruption can trigger inflammation and insulin resistance remains to be seen. 

Dr. Elks and her team will test if fat cells regulate the amount of free cytokine proteins to maintain homeostasis in fat tissue. They will test to see if continuous exposure of fat cells to OSM makes them less responsive to OSMR, thus causing them to become resistant to insulin. 

“I congratulate Dr. Elks on her lab’s recent discovery and the subsequent award to continue exploring it,” said Dr. John Kirwan, executive director of Pennington Biomedical. “This research is a perfect example of our ‘cells to society’ mantra, as we seek to explore the roots of obesity and open new avenues for how to best prevent and treat it.” 

Dr. Elks’ Matrix Biology lab studies communication networks on the cellular level that have been linked to insulin resistance, type 2 diabetes and a worsening of Crohn’s Disease in humans. The lab works to uncover methods to regulate adipose tissue function with the ultimate goal of developing better treatments for patients with metabolic diseases. 

About the Pennington Biomedical Research Center 
The Pennington Biomedical Research Center is at the forefront of medical discovery as it relates to understanding the triggers of obesity, diabetes, cardiovascular disease, cancer and dementia. The Center conducts basic, clinical, and population research, and is a campus of the LSU System. 
 
The research enterprise at Pennington Biomedical includes over 530 employees within a network of 44 clinics and research laboratories, and 13 highly specialized core service facilities. Its scientists and physician/scientists are supported by research trainees, lab technicians, nurses, dietitians, and other support personnel. Pennington Biomedical is a state-of-the-art research facility on a 222-acre campus in Baton Rouge.  

For more information, see www.pbrc.edu.  



Share12Tweet8Share2ShareShareShare2

Related Posts

SVTopo: Visualizing Complex Structural Variants

SVTopo: Visualizing Complex Structural Variants

October 9, 2025
Europe’s Largest Bats Hunt and Consume Migrating Birds Mid-Flight High Above the Ground

Europe’s Largest Bats Hunt and Consume Migrating Birds Mid-Flight High Above the Ground

October 9, 2025

Young Birds Acquire Vital Life Skills from Older Siblings and Flock Members, Study Finds

October 9, 2025

Innovative Biosensor Monitors Plant Immune Hormone Dynamics in Real Time

October 9, 2025

POPULAR NEWS

  • Sperm MicroRNAs: Crucial Mediators of Paternal Exercise Capacity Transmission

    1175 shares
    Share 469 Tweet 293
  • New Study Reveals the Science Behind Exercise and Weight Loss

    101 shares
    Share 40 Tweet 25
  • New Study Indicates Children’s Risk of Long COVID Could Double Following a Second Infection – The Lancet Infectious Diseases

    96 shares
    Share 38 Tweet 24
  • Ohio State Study Reveals Protein Quality Control Breakdown as Key Factor in Cancer Immunotherapy Failure

    81 shares
    Share 32 Tweet 20

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

Core Diversification with 1,2-Oxaborines: Versatile Platform

Exploring the Dose-Dependent Impact of Dissolved Biochar on C. elegans: Uncovering Physiological and Transcriptomic Changes

New Study Uncovers Genetic Connection to the Most Common Pediatric Bone Cancer

Subscribe to Blog via Email

Enter your email address to subscribe to this blog and receive notifications of new posts by email.

Join 63 other subscribers
  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.