Hippocampal Wiring Study Finds Graded Mossy Fiber Inputs and Targeted Inhibition
The hippocampus is often portrayed as a single memory machine, but a new connectomics study suggests that one of its most important circuits is organized...
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Palmitate Drives Liver Metastasis by Suppressing Neutrophils’ Antitumour Activity
Liver metastases are among the most difficult complications of advanced cancer. Unlike many other organs, the liver is continuously exposed to nutrients arriving from the...
Single-nucleus analysis reveals human fat-cell subsets with distinct metabolic profiles
White fat is often portrayed as a passive storage depot, a biological warehouse where excess energy is packed away for later use. A new study...
Ultrasound-Guided Nasojejunal Tube Placement Reduces Malposition and Radiation in Newborns
A bedside ultrasound technique is emerging as a potential alternative to repeated X-ray checks for placing nasojejunal feeding tubes in newborns, according to a multicenter...
Rethinking Blood Culture Timing Could Reduce NICU Antibiotic Exposure
A routine laboratory clock may hold the key to reducing unnecessary antibiotic exposure among newborns in intensive care. A new study in the Journal of...
Northeast China Farms Lack Soil Carbon’s Maize Benefits Seen in Trials
A finding that could reshape the global conversation about climate-smart agriculture is challenging one of the field’s most appealing assumptions: that increasing soil organic carbon...
Engineered lipid nanoparticles enable durable blood stem cell editing in humanized mice
A new lipid nanoparticle system has enabled researchers to genetically modify human haematopoietic stem and progenitor cells (HSPCs) inside humanized mice, addressing one of the...
Enhancing Interface Charge Transport Boosts Perovskite–CIGS Tandem Solar Cell Efficiency
Monolithic perovskite/Cu(In,Ga)Seâ‚‚ tandem solar cells have reached a new performance milestone, with researchers reporting a certified power conversion efficiency of 30.57% for a small-area device....
Human Activity More Than Doubles Arctic Fire Occurrence
The Arctic is often portrayed as a wilderness ruled almost entirely by temperature, drought, and the slow movement of climate systems. But a new study...
Study reveals HHV-8-driven immune regulation in HIV-associated and classic Kaposi sarcoma
Kaposi sarcoma is not simply a tumour made of abnormal blood vessels. It is a complex tissue ecosystem in which infected cells, immune cells, endothelial...
TMEM135 Deficiency Prevents Intestinal Fat Buildup Through ELOVL6-Driven PPARα Lipid Oxidation
A molecular switch that helps the intestine manage incoming fat may have been identified in an unexpected place: the activity of a protein called TMEM135....
Light activity may reduce stroke and death risk in atrial fibrillation
A large Norwegian study suggests that even modest physical activity may help reduce the risk of stroke and premature death in people with atrial fibrillation,...
Experimental drug weaponizes cancer’s sugar addiction against tumors
Cancer cells are often described as metabolic opportunists, consuming extraordinary amounts of glucose to sustain rapid growth. A new experimental drug takes advantage of that...
THC May Help End Trauma-Related Nightmares, Study Suggests
For people living with post-traumatic stress disorder (PTSD), sleep can become a nightly reenactment of catastrophe. Traumatic memories may return as vivid, emotionally overwhelming nightmares,...
Warming Climate Drives Butterflies Worldwide Into New Territories
Butterflies may be among the most visible indicators of a rapidly changing planet. Their delicate wings suggest fragility, but their populations can reveal large-scale ecological...