Pediatric Left Ventricular Noncompaction: From Trabeculation Phenotype to Prognosis
A striking pattern seen on cardiac scans has become one of the most debated findings in pediatric cardiology: a left ventricle with unusually prominent muscular...
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CaMK4 Fuels Psoriasis-Driving Th17 Responses Through the STAT3-RORγt Pathway
Psoriasis is often described as a skin disease, but its deepest biology unfolds across the immune system. Beneath the familiar plaques, scaling and redness lies...
Living Cellular Assemblies Offer New Therapeutic Possibilities
A new review in Nature Reviews Bioengineering presents cellular assemblies as a potential new class of “living therapeutics” — biological systems built from organized groups...
Study Maps Lymph Node Metastases, Optimizes Dissection for Resectable Mucinous Lung Adenocarcinoma
A rare form of lung cancer is prompting surgeons to rethink one of the most consequential decisions in thoracic oncology: how many lymph nodes should...
Ruptured Hepatic Artery Aneurysm Into Biliary Tract During LVAD Support Successfully Embolized
A rare and potentially fatal complication of long-term mechanical circulatory support has been successfully treated without open surgery, according to a case report published in...
AdaG-Net: A Multimodal Model for Mortality Prediction in Acute Respiratory Distress Syndrome
Acute respiratory distress syndrome, or ARDS, can transform a respiratory infection, trauma, or systemic illness into a rapidly evolving medical emergency. The syndrome is marked...
Study finds age-related vulnerability to paraquat neurotoxicity in male rats
A new investigation into paraquat-induced neurotoxicity in male Wistar rats is drawing attention to a question with major implications for environmental health: does age determine...
Beyond Pedal Kickback: Classifying Crank Torque in Downhill Mountain Biking
A new study is challenging one of mountain biking’s most persistent explanations for uncomfortable pedal feedback: the idea that pedal kickback is usually responsible. Researchers...
Serum Proteomics Identifies Shared Signatures in Hypermobile Ehlers-Danlos and Spectrum Disorders
A new serum-profiling study is bringing molecular evidence to one of the most difficult diagnostic questions in connective-tissue medicine: how closely are hypermobile Ehlers–Danlos syndrome...
Metal–organic frameworks selectively capture heavy metals and recover rare earth elements
Water treatment is entering an era in which removing pollutants is no longer enough. The next generation of purification technologies must identify specific contaminants, withstand...
AI App Personalizes Audio Guidance for Safer Outdoor Navigation Among Blind People
Blindness and moderate-to-severe visual impairment affect an estimated 340 million people worldwide, transforming an ordinary walk through a neighborhood into a complex exercise in perception,...
Blocking cyclin D1–CDK6 curbs inflammatory senescence genes and age-related functional decline
A familiar cell-cycle protein may be helping aging cells broadcast inflammatory signals throughout the body, according to a new study published in Nature Aging. Researchers...
Multiomic profiling reveals AML molecular subtypes and potential treatment targets
Acute myeloid leukemia, or AML, is often described as a single disease, but that label conceals a sprawling collection of biologically distinct cancers. Two patients...
Spatial transcriptomics reveals dynamic cellular programs driving human heart transplant rejection
A heart transplant can restore circulation, reverse advanced heart failure and give patients years of life, but the new organ remains under constant surveillance by...
Study reveals how PRC2 guides preimplantation development and primordial germ cell fate
A new study has revealed that the epigenetic regulator PRC2 performs different, stage-specific jobs during the earliest phases of mammalian embryonic development. The findings, reported...