Hypercontractile embryos from older female mice experience implantation failure
A hidden mechanical failure inside the earliest stages of life may help explain why fertility declines so sharply as females enter their mid-30s. A study...
NEWS INDEX
European summit plant communities show widespread thermophilization, weakly linked to climate warming
Europe’s highest plant communities are getting warmer in character, but not necessarily because the climate above them is warming in lockstep. A new study published...
Scientists design tissue-specific mammalian enhancers that function in mouse embryos
A new study reports a step toward treating mammalian gene regulation as an engineering problem: rather than searching through the genome for enhancers that happen...
Long-Term Ambient Air Pollution Exposure Linked to Global Cancer Burden
A new global analysis has linked long-term exposure to three widespread air pollutants with millions of newly diagnosed cancer cases, offering one of the most...
Disrupted Cellular RNA Balance Drives MDA5 Activation During Viral Infection
For decades, antiviral immunity has been described as a molecular surveillance system built to distinguish the genetic material of invading viruses from the RNA normally...
Atomic electron tomography reveals crystal nucleation and growth in high-entropy alloys
High-entropy alloys are built from an unusual recipe: instead of relying on one dominant element with smaller additions, they combine several principal elements in comparable...
Experts develop consensus approach for spatially aware clustering beyond benchmarking
Spatial biology has created a problem that conventional clustering benchmarks were never designed to solve. In technologies such as spatial transcriptomics, researchers do not merely...
Ultrafast Electron Diffraction Achieved Using a Laser Wakefield Accelerator’s MeV Electron Source
Ultrafast electron diffraction has taken a major step toward becoming faster, smaller and more precisely synchronized. In a new proof-of-principle experiment, researchers generated electron beams...
Dipole glass enables cryogenic energy storage through unit-cell polar disorder
A new approach to energy storage could keep advanced electronics running in environments where conventional batteries and capacitors begin to fail. Researchers have developed a...
Wigner Polarons Reveal Wigner Crystal Dynamics in Monolayer Semiconductors
Electrons Freeze into a Quantum Lattice—and Light Can Now Make Them Move For decades, Wigner crystals have represented one of the most striking predictions in...
Integrated 2D Photosensitive Memory Enables Direct Conversion of Light into Tokens
Artificial intelligence may soon begin processing images before digital data ever reaches a conventional computer. In a study published in Nature Sensors, researchers report a...
Scientists Identify Factors Governing Human β2-Adrenergic Receptor–β-Arrestin Complex Assembly
A new study published in Nature Structural & Molecular Biology is clarifying how one of the most important signaling complexes in human cells is assembled....
LAPO Uses LLMs to Optimize Adaptive Query Paths in Key-Value Stores
Researchers have unveiled a new artificial intelligence framework designed to make complex database searches dramatically faster, combining large language models with adaptive query optimization inside...
Benchmarking ESM2 Across Scales for Predicting Viral Entry Proteins
Viral entry proteins are among the most consequential molecules in infectious disease biology. Positioned at the interface between a virus and its host, they recognize...
Single-cell RNA sequencing maps gonadal changes during sex reversal in orange-spotted grouper
A single-cell transcriptomic study of the orange-spotted grouper, Epinephelus coioides, is offering an unprecedented view of how a fish gonad reorganizes itself during hormone-induced sex...