Chemigenetic Biosensor Tracks Endogenous Ras Activity in Living Cells During Drug Research
Ras, one of the cell’s most influential molecular switches, has become the focus of a new live-cell imaging technology designed to reveal where and when...
NEWS INDEX
Chronic Kidney Disease in Women: Global Burden and Metabolic-Cardiovascular Connections
Chronic kidney disease has become a rapidly expanding global health threat for women, with the number of women living with the condition rising from approximately...
Molecular Self-Assembly Enables High-Throughput DNA Fragment Synthesis from Overlapping Oligonucleotides
DNA synthesis has become one of synthetic biology’s most powerful enabling technologies—and one of its most persistent bottlenecks. Although researchers can now design entire pathways,...
Dynamic duo weaves hierarchical DNA materials using two classes of biomolecular nanomachines
Researchers in Japan have developed a molecular construction system that uses two chemically powered biomolecular machines to build interconnected DNA networks from the bottom up....
Wiley Launches First Spectral Analysis API Portfolio to Speed Substance Identification
Wiley has launched a new portfolio of application programming interfaces designed to bring spectral databases, chemical-analysis algorithms, and predictive models directly into laboratory instruments, research...
Wildlife Disease Increases with Urban Density, Habitat Connectivity and Climate Change
Coyotes are becoming an increasingly important signal of how urban growth, fragmented habitats and a warming climate are reshaping wildlife disease. A new multi-city study...
Localized recurrent connections control neural activity dimensionality across brain regions
A new study suggests that the brain’s neural activity may be governed by a surprisingly simple principle: strong, highly localized feedback connections can sharply limit...
Global study finds traumatic brain injury causes vary widely
Every year, traumatic brain injury kills nearly 5 million people worldwide and affects tens of millions more, yet a new global study suggests that the...
Ambient Noise Linked to Physiological Changes in Single-Ventricle Newborns After Norwood Surgery
A Newborn’s First Heart Surgery May Leave the Brain and Body Vulnerable to Hospital Noise For newborns born with only one functional pumping chamber, the...
Thermal justice could make urban heat adaptation fairer as cities grow hotter
As cities confront increasingly frequent and severe heatwaves, scientists are urging authorities to rethink what it means to protect people from extreme temperatures. Conventional heat-health...
IOF Names New Editor-in-Chief for Osteoporosis International’s European Office
The International Osteoporosis Foundation (IOF) has appointed Professor René Rizzoli as the next Editor-in-Chief for the European Office of Osteoporosis International and Archives of Osteoporosis,...
Aging Alters Skin Gene Activity, Fueling Inflammation
Barcelona researchers have identified a molecular mechanism that may help explain why ageing skin develops a persistent, low-grade inflammatory state. The study, led by Guiomar...
Generating and transferring nitrenes enables unnatural biosynthesis in living cells
Nitrenes are among chemistry’s most useful and most difficult-to-control intermediates. These nitrogen-centred species can insert into carbon–hydrogen bonds, add across carbon–carbon double bonds, and rearrange...
Neighborhood social and economic opportunity predicts neurodevelopmental outcomes in high-risk infants
For infants who leave neonatal intensive care, the hospital discharge is not the end of a medical journey. It is the beginning of a long...
How Body Mass Index and Waist Size Affect Mortality in Older Adults
A large analysis of older adults in the United States is challenging one of the most familiar assumptions in public health: that a higher body...