Insights into the diagnosis and treatment brain cancer in children
Credit: Kanazawa University Ependymoma is a rare form of brain cancer that implicates children and is often tricky to diagnose. Since effective treatment options can...
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Overcoming primary resistance to checkpoint inhibition with selective inhibitor of TGFβ1
Selective inhibition of latent TGFβ1 activation with SRK-181 has demonstrated an improved preclinical safety profile compared to conventional inhibitors of TGFβ signalingCredit: Scholar Rock Retrospective...
Experimental model mimics early-stage myogenic deficit in boys with DMD
Large spike in TGFβ activity in injured muscle triggers a downward spiral leading to muscle degeneration and failed muscle regenerationCredit: Children's National Hospital Boys with...
Experiments in mice and human cells shed light on best way to deliver nanoparticle therapy for cancer
Credit: Robert Ivkov, Ph.D. Researchers in the cancer nanomedicine community debate whether use of tiny structures, called nanoparticles, can best deliver drug therapy to tumors...
Lipid helps heal the eye’s frontline protection
Credit: Phil Jones, Senior Photographer, Augusta University A species of a lipid that naturally helps skin injuries heal appears to also aid repair of common...
Despite failures, chemo still promising against dangerous childhood brain cancer, DIPG
Credit: University of Colorado Cancer Center The pediatric brain cancer known as diffuse intrinsic pontine glioma (DIPG) is almost uniformly fatal. In part, this is...
Edmonton company Entos developing DNA vaccine against COVID-19
University of Alberta cancer researcher John Lewis's health-care biotechnology company is working on a vaccine to be delivered directly into patients' cells, driving a protective...
OSU research paves way to improved cleanup of contaminated groundwater
Credit: OSU College of Engineering CORVALLIS, Ore. - Beads that contain bacteria and a slow-release food supply to sustain them can clean up contaminated groundwater...
Solving a 50-year-old puzzle in signal processing, part two:
Engineers explore algorithm's capabilities in special cases 'on the unit circle'Credit: Figure courtesy of Alexander Stoytchev. AMES, Iowa - Iowa State University's Alexander Stoytchev says...
A critical enzyme for sperm formation could be a target for treating male infertility
The protein, SKP1, drives a key transition step in male meiosis, the type of cell division process that results in sperm, School of Veterinary Medicine...
Renewable energy developments threaten biodiverse areas
Credit: Francisca Hidalgo More than 2000 renewable energy facilities are built in areas of environmental significance and threaten the natural habitats of plant and animal...
A small forage fish should command greater notice, researchers say
UMass Amherst, more than 20 scientists urge greater effort to gather sand lance dataCredit: UMass Amherst/Keenan Yakola AMHERST, Mass. - A slender little fish called...
Eclectic rocks influence earthquake types
Credit: IODP JRSO New Zealand's largest fault is a jumble of mixed-up rocks of all shapes, sizes, compositions and origins. According to research from a...
Found in mistranslation
Researchers from the National Centre for Biological Sciences, Bangalore, have found that global mistranslation of proteins increases cell survival under stress in E. coliCredit: Pranjal...
Those living in rural areas, uninsured or on Medicaid less likely to receive recommended lung cancer treatment
Keck Medicine of USC study reveals that socioeconomic status disparities cause patients to miss out on treatment that improves five-year lung cancer survival rateCredit: Ricardo...
