Florida Cane Toad: Complex Spread and Selective Evolution
Invasive species offer a unique window into the mechanisms of rapid evolution and adaptation, especially as they colonize new environments that often differ drastically from...
NEWS INDEX
Exploring Decision-Making in Dementia Caregivers’ Mobility
In a groundbreaking initiative focusing on the nuanced dynamics of caregiver decision-making, a recent study protocol outlines a randomized vignette study that employs message framing...
Succinate Receptor 1 Limits Blood Cell Formation, Leukemia
In a groundbreaking study set to reshape our understanding of blood diseases and cancer biology, researchers have unveiled the pivotal role of succinate receptor 1...
Palmitoylation of Tfr1 Drives Platelet Ferroptosis and Exacerbates Liver Damage in Heat Stroke
Heat stroke (HS), a perilous medical emergency marked by extreme hyperthermia, presents an ongoing challenge in clinical medicine due to its frequent association with multiorgan...
Oxygen-Enhanced Dual-Section Microneedle Patch Improves Drug Delivery and Boosts Photodynamic and Anti-Inflammatory Treatment for Psoriasis
A groundbreaking advancement in psoriasis treatment has been unveiled through the recent publication in Acta Pharmaceutica Sinica B, highlighting the development of an innovative oxygen-boosted...
Scientists Identify SARS-CoV-2 PLpro and RIPK1 Inhibitors Showing Potent Synergistic Antiviral Effects in Mouse COVID-19 Model
A Breakthrough in COVID-19 Therapeutics: Synergistic Targeting of SARS-CoV-2 PLpro and Host RIPK1 Yields Promising Results in Preclinical Models The global battle against COVID-19 continues...
Neg-Entropy: The Key Therapeutic Target for Chronic Diseases
In a groundbreaking publication in Acta Pharmaceutica Sinica B, researchers have introduced a transformative paradigm for understanding and treating chronic diseases by focusing on the...
Multidisciplinary Evidence-Based Guidelines for Therapeutic Drug Monitoring of Biologics in Inflammatory Bowel Disease
Therapeutic Drug Monitoring of Biologics in Inflammatory Bowel Disease: A Landmark Evidence-Based Guideline In the ever-evolving landscape of inflammatory bowel disease (IBD) management, biologic therapies...
Early Tuberculosis Treatment Lowers Sepsis Mortality in People with HIV
Sepsis remains one of the most formidable challenges in global health, representing a critical condition where the body’s overwhelming immune response to infection leads to...
Deep Learning Uncovers Tetrahydrocarbazoles as Potent Broad-Spectrum Antitumor Agents with Click-Activated Targeted Cancer Therapy Approach
In a groundbreaking advancement in the field of oncology drug discovery, researchers have harnessed the power of deep learning to identify and develop novel tetrahydrocarbazole...
Structure-Guided Development of Picomolar Macrocyclic Inhibitors Targeting TRPC5 Channels with Antidepressant Effects
In a groundbreaking development at the frontier of neuropharmacology and ion channel research, a team of scientists has unveiled a novel class of macrocyclic inhibitors...
Breakthrough in Environmental Cleanup: Scientists Develop Solar-Activated Biochar for Faster Remediation
In a pioneering advance that could redefine environmental restoration and pollutant mitigation strategies, researchers have unveiled a novel technique to engineer biochar with vastly superior...
Comprehensive Global Analysis: Merging Finance, Technology, and Governance Essential for Just Climate Action
A recent global review underscores an urgent and critical understanding of climate change: addressing this monumental challenge extends far beyond financial support or innovative technologies...
Newly Discovered Limonoid DHL-11 from Munronia henryi Targets IMPDH2 to Combat Triple-Negative Breast Cancer
A groundbreaking study recently published in the prestigious journal Acta Pharmaceutica Sinica B has unveiled a promising new therapeutic candidate, DHL-11, a novel prieurianin-type limonoid...
Stabilized MERS-CoV Spike Nanoparticle Vaccine Shows Promise
In a groundbreaking advancement in the global fight against coronaviruses, a team of researchers has unveiled a highly promising vaccine candidate targeting Middle East Respiratory...
