• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
Sunday, August 24, 2025
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Health

New technique to fast-track pain research

Bioengineer by Bioengineer
January 21, 2021
in Health
Reading Time: 2 mins read
0
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

Pioneering sensory neuron replication

IMAGE

Credit: Flinders Foundation

Scientists have for the first time established a sensory neuron model able to mass-reproduce two key sensory neuron types involved in pain sensation, enabling the easy generation of large numbers of the cells to fast-track chronic pain research.

In research applications usually sensory neurons need to be isolated from animals. They represent a wide variety of different cell types, making it difficult to collect and isolate large quantities of pain sensing neurons.

Using a new technique, researchers at Flinders University have found a way to reproduce millions of the cells, providing ample resources for the simultaneous testing of thousands of samples or potential drug libraries.

“Our model replicates sensory neurons found in bundles called dorsal root ganglia next to the spinal cord. These house the majority of the sensory fibres in the whole body that are capable of detecting heat, noxious chemicals and pressure, itch and cold,” says Flinders University’s Dr Dusan Matusica, who led the new study.

Dr Matusica says these neurons are involved in collating and transmitting all the signals from the body to the spinal cord, and then the brain.

“Scientists have long known that a subgroup of these neurons is critical in transmitting signals that lead to feelings of pain, and that changes in their signalling leads to the development of chronic pain.

“But together with challenges in isolating sufficient quantities of the neural cells, we have the additional challenge of cells dying in the isolation process.

“Our model means that for the first time, we can easily generate pure populations of these two types of sensory cells in culture, providing the opportunity to get further insights into their function.”

Dr Matusica says this new finding has significant implications for researchers around the world, with billions of the cells able to the cultured in as short a time as a week if needed, substantially reducing scientists’ reliance on animals in the initial discovery phases of research projects.

The multidisciplinary research team has also genetically sequenced the two neural cells in their entirety, meaning researchers around the world can quickly and easily determine whether they are suitable for their studies.

###

The article, Differentiation of the 50B11 dorsal root ganglion cells into NGF and GDNF responsive nociceptor subtypes (2020), by D Matusica, J Canlas, AM Martin, Y Wei, S Marri, A Erickson, CM Barry, SM Brierley, OG Best, MZ Michael, NH Voelcker, DJ Keating and RV Haberberger has been published in Molecular Pain DOI: 10.1177/1744806920970368

Media Contact
Dr Dusan Matusica
[email protected]

Related Journal Article

http://dx.doi.org/10.1177/1744806920970368

Tags: cancerCell BiologyMedicine/HealthneurobiologyPain
Share12Tweet8Share2ShareShareShare2

Related Posts

Real-World Study: Efficacy of Loxenatide Plus Insulin

Real-World Study: Efficacy of Loxenatide Plus Insulin

August 24, 2025
Link Between hs-CRP/HDL-C Ratio and Diabetes Risk

Link Between hs-CRP/HDL-C Ratio and Diabetes Risk

August 24, 2025

Revolutionizing Drug Interaction Prediction with Graph Networks

August 24, 2025

Royal Jelly Eases Gemcitabine Ovarian Toxicity in Rats

August 24, 2025
Please login to join discussion

POPULAR NEWS

  • blank

    Molecules in Focus: Capturing the Timeless Dance of Particles

    141 shares
    Share 56 Tweet 35
  • Breakthrough in Computer Hardware Advances Solves Complex Optimization Challenges

    115 shares
    Share 46 Tweet 29
  • New Drug Formulation Transforms Intravenous Treatments into Rapid Injections

    115 shares
    Share 46 Tweet 29
  • Neuropsychiatric Risks Linked to COVID-19 Revealed

    81 shares
    Share 32 Tweet 20

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

Influence of Diet and Rumen Source on Fermentation

Early Dinosaur Skull Lesions Suggest Aggressive Behavior

Ganoderma Lucidum Polysaccharides Boost Memory, Gut Health

  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.