• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • CONTACT US
Saturday, March 25, 2023
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • CONTACT US
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • CONTACT US
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News

New study seeks to use human serum to detect heart attacks

Bioengineer by Bioengineer
December 13, 2016
in Science News
Reading Time: 2 mins read
0
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram
IMAGE

Credit: UNIST

Heart disease is the leading cause of death for both men and women. Therefore, a fast and reliable diagnosis of heart attack is urgently needed.

A new study, led by Prof. Jaesung Jang (School of Mechanical and Nuclear Engineering) has developed an electrical immunosensor to detect the acute myocardial infarction, also known as a heart attack within a minute. The system works by measuring the level of cardiac troponin I (cTnI), a protein that is excreted by the heart muscle into the blood following a heart attack.

Prof. Jang states, "This new immunosensor is constructed in a different way than any other sensor." He adds, "Owing to the new design of this immunosensor, this device is able to rapidly diagnose the level of heart attacks at the point of care."

A schematic diagram of the SWCNT electrical immunosensor with two pairs of concentration and detection electrodes.A schematic diagram of the SWCNT electrical immunosensor with two pairs of concentration and detection electrodes.

Using just a single droplet of blood, this immunosensor detects the target protein present in the blood serum following a heart attack and provides a result in 1 minute.

In the study, dielectrophoretic (DEP) forces have been applied to attract the target protein. The incubation time required for the detection is decreased through DEP-mediated biomarker concentration, in which the target protein is attracted onto the sensing areas via electrical forces. Therefore, the dielectrophoretic concentration of cTnI reduced the incubation time required from 60 min to 1 min.

Chang-Ho Han (School of Mechanical and Nuclear Engineering), a combined master's-doctoral student in Prof. Jang's group notes, "The level of cTnI within a single droplet of blood serum is not great." He continues, "However, we were able to attract the target protein onto the sensing areas via electrical forces, thereby greatly improvingdetection time and detection limit."

Image shown above is the core material used for the new sensor detects proteins in the blood stream following a heart attack, providing results in just 10 minutes.Image shown above is the core material used for the new immunosensor that detects proteins in the blood stream following a heart attack, providing results in just 1 minute.

According to the research team, this novel immunosensor holds considerable potential for use as a platform for sensing distinct types of proteins, along with the feasibility of miniaturization and integration for biomedical diagnosis.

The findings of the research have been published in the August issue of the prestigious biotechnology journal Biosensors & Bioelectronics.

###

This work has been supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education and by the 2016 Research Fund of UNIST.

Journal Reference: Abhinav Sharma, Chang-Ho Han, and Jaesung Jang, "Rapid electrical immunoassay of the cardiac biomarker troponin I through dielectrophoretic concentration using imbedded electrodes." Biosensors and Bioelectronics, 2016.

Media Contact

JooHyeon Heo
[email protected]
82-522-171-223

home

############

Story Source: Materials provided by Scienmag

Share12Tweet7Share2ShareShareShare1

Related Posts

Picture1.png

Is early rhythm control in atrial fibrillation care cost-effective?

March 25, 2023
Transitions of low and high-entropy metal tellurides.

“Glassiness” and “blurriness” might explain the behavior of high-entropy superconductors

March 25, 2023

Illinois Tech Assistant Professor Ren Wang receives prestigious National Science Foundation Award

March 24, 2023

New type of entanglement lets scientists ‘see’ inside nuclei

March 24, 2023
Please login to join discussion

POPULAR NEWS

  • ChatPandaGPT

    Insilico Medicine brings AI-powered “ChatPandaGPT” to its target discovery platform

    65 shares
    Share 26 Tweet 16
  • Northern and southern resident orcas hunt differently, which may help explain the decline of southern orcas

    44 shares
    Share 18 Tweet 11
  • Skipping breakfast may compromise the immune system

    43 shares
    Share 17 Tweet 11
  • Insular dwarfs and giants more likely to go extinct

    35 shares
    Share 14 Tweet 9

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

Is early rhythm control in atrial fibrillation care cost-effective?

“Glassiness” and “blurriness” might explain the behavior of high-entropy superconductors

Illinois Tech Assistant Professor Ren Wang receives prestigious National Science Foundation Award

Subscribe to Blog via Email

Enter your email address to subscribe to this blog and receive notifications of new posts by email.

Join 48 other subscribers
  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In