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Home NEWS Science News Health

Neurobiology and Chemistry of Pain and Addiction Symposium

Bioengineer by Bioengineer
April 22, 2019
in Health
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World-renowned neurobiologists and leaders in chemistry will discuss the brain circuits underlying acute and chronic pain, reward, motivation and addiction, as well as the development of chemical probes as potential novel therapies

TUCSON, Ariz. – World-renowned researchers will gather for the Neurobiology and Chemistry of Pain and Addiction Symposium at the University of Arizona Health Sciences campus on Wednesday, April 24, 8 a.m. – 6:30 p.m., in the Thomas W. Keating Bioresearch Building, Room 103, 1657 E. Helen St., Tucson, Ariz., 85719.

The symposium is co-sponsored by the University of Arizona College of Medicine – Tucson Department of Pharmacology and Interim Dean Irving Kron, MD.

Prominent neurobiologists will present state-of-the-art understanding of the often overlapping brain circuits underlying acute and chronic pain, reward, motivation and addiction.

Leaders in chemistry will highlight the progress in the development of chemical probes that not only improve understanding of neurobiology but also are being advanced as potential novel therapies.

Special recognition will be given to Rao S. Rapaka, PhD, chief, Chemistry and Pharmacology Research Branch, Division of Neuroscience and Behavior, National Institute on Drug Abuse for promoting advances in the treatment of pain and addiction.

Topics and presenters include:

8:15 a.m. – 9:00 a.m. The Opioid Crisis Teaches

Jane Ballantyne, MD, University of Washington Medical Center, anesthesiology and pain medicine

9:00 a.m. – 9:30 a.m. The Neurobiology of Opioid Analgesia and Reward

Howard Fields, MD, PhD, professor emeritus, neurology, University of California, San Francisco

10:00 a.m. – 10:30 a.m. Kappa opioid antagonists as pain therapeutics

Frank Porreca, PhD, associate head and professor, UA Department of Pharmacology; UA professor, anesthesiology

10:30 a.m. – 11:00 a.m. Discovery and development of CYM53093, a novel, selective and short-acting kappa opioid receptor antagonist

Edward Roberts, PhD, professor, Scripps Research Institute, La Jolla

11:00 a.m. – 11:30 p.m. Long-lasting peripherally restricted kappa opioid agonists as pain therapeutics

Pierre Riviere, PhD, founder and CEO, Peptide Logic

11:30 p.m. – Noon Targeting multiple receptor systems through multivalent ligands to improve chronic pain therapy

Victor Hruby, UA Regents’ Professor Emeritus, Department of Chemistry and Biochemistry

John Streicher, PhD, UA assistant professor, pharmacology

1:30 p.m. – 2:00 p.m. Separating analgesic efficacy from physical dependence by targeting the endocannabinoid system

Andrea Hohmann, PhD, Gil Chair and professor, Department of Psychological and Brain Sciences, Indiana University Bloomington

2:00 p.m. – 2:30 p.m. Structure and Function of Cannabinoid Receptors

Alexandros Makriyannis, PhD, professor, chemistry and chemical biology, George D Behrakis Chair of Pharmaceutical Biotechnology, Center for Drug Discovery, Northeastern University

2:30 p.m. – 3:00 p.m. Optimizing cannabinoid-based medicines for epilepsy and beyond

Nephi Stella, PhD, professor, Department of Pharmacology, University of Washington

3:00 p.m. – 3:30 p.m. Therapeutic application of cannabinoid agonists

Todd Vanderah, PhD, department head and professor, UA Department of Pharmacology; UA professor, anesthesiology and neurology; professor, UA BIO5 Institute

4:00 p.m. – 4:30 p.m. S1PR1 antagonists as novel therapeutics for pain

Daniela Salvemini, PhD, professor, pharmacological and physiological science, Saint Louis University School of Medicine

4:30 p.m. – 5:00 p.m. Allosteric regulation of sodium channel NaV1.7 for pain therapeutics

Rajesh Khanna, PhD, UA professor, pharmacology and anesthesiology; professor, UA BIO5 Institute

5:00 p.m. – 5:15 p.m. Targeting spinal neurotensin system by a snail toxin for pain

Amol Patwardhan, PhD, MBBS, UA assistant professor, anesthesiology and pharmacology

5:15 p.m. – 5:30 p.m. Light therapy for treatment of pain

Mohab Ibrahim, PhD, MD, UA associate professor, anesthesiology and pharmacology

5:30 p.m. – 5:45 p.m. Migraine, blood-brain barrier and therapeutic opportunities

Tally Largent-Milnes, PhD, UA assistant professor, pharmacology; assistant professor, UA BIO5 institute

5:45 p.m. – 6:15 p.m. Opposing roles of mu and kappa opioid circuits in descending pain modulation

Edita Navratilova, PhD, UA research assistant professor, pharmacology

6:15 p.m. – 6:30 p.m. Genetic and Pharmacological Validation of CRMP2 Phosphorylation as a Novel therapeutic Target for Neuropathic Pain

Aubin Moutal, PhD, UA research assistant professor, pharmacology

###

Media Contact
Jean Spinelli
[email protected]
https://opa.uahs.arizona.edu/newsroom/news/2019/neurobiology-and-chemistry-pain-and-addiction-symposium-april-24

Tags: AddictionDrugsMedicine/HealthPainPharmaceutical ChemistryPharmaceutical Science
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