Ishimoto, Y., Menezes, L.F., Nakaya, N. et al. Deletion of ARPKD-associated Pkhd1 gene in mice results in decreased Tfap2b expression and eye abnormalities.
Nat Commun (2026).
Tags: ARPKD mouse modelARPKD-associated gene functioncongenital eye abnormalitiesdevelopmental eye defects in miceeye abnormalities in genetic mouse modelsgene knockout studies in micePkhd1 and Tfap2b gene regulationPkhd1 gene deletion effectspolycystic kidney disease geneticspolycystic kidney disease researchrenal and ocular phenotypes in ARPKDTfap2b gene expression changes
