CU Anschutz study shows vaping nicotine while pregnant may impact fetal development

Researchers at the University of Colorado Anschutz Medical Campus have found that vaping nicotine during pregnancy may be no safer for a developing fetus than smoking cigarettes. The study suggests that vaping nicotine interferes with fetal bone and lung development.

The paper was published in Developmental Biology.

“Pregnant women are increasingly turning to vaping with electronic cigarettes as a perceived safer alternative to cigarettes. However, nicotine disrupts fetal development, suggesting that, like cigarette smoking, nicotine vaping may be detrimental to the fetus.,” said  Emily Bates, PhD, an associate professor at the University of Colorado School of Medicine. “Nicotine passes through the placenta to fetal circulation where it can accumulate to reach higher levels than in the maternal plasma. This disrupts the development of multiple organs and systems.”

Using an animal model, Bates and her team discovered that even low levels of e-cigarette vapor during pregnancy inhibits growth.

“Those that were exposed to vaping ended up with smaller and shorter bones during their development. Additionally, we found that the nicotine impacts which genes are turned on in the fetal lung,” said Bates who collaborated with Eszter Vlader, PhD,  an assistant professor at the University of Colorado School of Medicine.

The findings indicate that vaping nicotine during pregnancy can be detrimental to the baby. Bates hopes this study will encourage those hoping to conceive to be more cautious when it comes to nicotine use.

“The popularity of vaping among young people, the addictive nature of nicotine, and the lack of perceived risk suggests that vaping during pregnancy will likely increase over time,” Bates said. “Identifying the effects of maternal e-cigarette exposure on fetal development is essential to inform public health messaging and protect the health of the baby.”

Graduate student Yunus Ozekin, who works in Bates’ Lab, also assisted with the study.

About the University of Colorado Anschutz Medical Campus

The University of Colorado Anschutz Medical Campus is a world-class medical destination at the forefront of transformative science, medicine, education and patient care. The campus encompasses the University of Colorado health professional schools, more than 60 centers and institutes, and two nationally ranked independent hospitals – UCHealth University of Colorado Hospital and Children’s Hospital Colorado – that treat more than two million adult and pediatric patients each year. Innovative, interconnected and highly collaborative, the University of Colorado Anschutz Medical Campus delivers life-changing treatments, patient care and professional training and conducts world-renowned research fueled by over $690 million in research grants. For more information, visit www.cuanschutz.edu.