• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
Tuesday, October 28, 2025
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Cancer

Cancer drug insight tactic could spell double trouble for tumours

Bioengineer by Bioengineer
November 1, 2018
in Cancer
Reading Time: 2 mins read
0
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram
IMAGE

Credit: Mar Carmena and Emma Peat

A new way of identifying potential cancer drugs could streamline the development of therapies, following a discovery by scientists.

Researchers have devised a way to screen potential drug compounds to select those that interfere with tumour cells in two ways.

Their study seeks to build on an existing approach of identifying drugs that target an essential protein in cancer cells, known as telomerase.

Scientists hope to identify drugs that not only inhibit this protein but also induce errors when cancer cells divide packages of their DNA – known as chromosomes – to form new cells.

An attack on two fronts could prevent cancerous cells from growing, and therefore kill tumours.

Researchers at the University of Edinburgh, the Institute Curie in Paris, the National Cancer Institute of the US and the Kazusa DNA Institute of Japan tested drug compounds using artificial human chromosomes with in-built fluorescent markers.

This allowed the team to easily detect when and how often drug treatment caused the loss of chromosomes.

Drugs identified in this way were then tested in different types of cancer cells, to investigate exactly how they were able to disrupt chromosome division at a high rate.

Researchers hope these newly identified drugs can inform development of more effective therapies.

The study, published in Cancer Research, was supported by Wellcome, the US National Institutes of Health, and the Government of Japan.

Professor William C Earnshaw, of the University of Edinburgh's School of Biological Sciences, who participated in the study, said: "Our approach enables the selection of drug compounds that disrupt normal division of cancer cells. Our hope is that this can result in the development of more effective therapies to target tumours."

Dr Mar Carmena, of the University of Edinburgh's School of Biological Sciences, who also took part in the study, said: "We hope our two-pronged approach can prove useful in targeting a range of cancers using newly selected, more efficient drugs."

###

Media Contact

Catriona Kelly
[email protected]
44-779-135-5940
@edinunimedia

http://www.ed.ac.uk

Original Source

https://www.ed.ac.uk/news/2018/cancer-drug-insight-could-lead-to-new-therapies http://dx.doi.org/10.1158/0008-5472.CAN-18-0894

Share12Tweet8Share2ShareShareShare2

Related Posts

Exploring Non-Contrast Transperineal Ultrasound in Pediatric Care

October 28, 2025

Remote Radiology’s Surprising Impact on Greenhouse Gas Emissions

October 28, 2025

Study Finds Connection Between Outdoor Air Pollution and Increased Breast Cancer Risk

October 28, 2025

Checkpoint Inhibitors Plus Antiangiogenics in Liver Cancer

October 27, 2025
Please login to join discussion

POPULAR NEWS

  • Sperm MicroRNAs: Crucial Mediators of Paternal Exercise Capacity Transmission

    1287 shares
    Share 514 Tweet 321
  • Stinkbug Leg Organ Hosts Symbiotic Fungi That Protect Eggs from Parasitic Wasps

    310 shares
    Share 124 Tweet 78
  • ESMO 2025: mRNA COVID Vaccines Enhance Efficacy of Cancer Immunotherapy

    198 shares
    Share 79 Tweet 50
  • New Study Suggests ALS and MS May Stem from Common Environmental Factor

    135 shares
    Share 54 Tweet 34

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

Link Between Academic Success and Internalizing Disorders

N-glycosylation of IgG: A Stroke Risk Predictor

The Importance of Body Clocks for Heart Health

Subscribe to Blog via Email

Enter your email address to subscribe to this blog and receive notifications of new posts by email.

Join 67 other subscribers
  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.