• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
Monday, October 20, 2025
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Health

Boron nitride nanofilms for protection from bacterial and fungal infections

Bioengineer by Bioengineer
October 20, 2020
in Health
Reading Time: 3 mins read
0
IMAGE
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

IMAGE

Credit: Sergey Gnuskov/NUST MISIS

NUST MISIS material scientists have presented antibacterial nano-coatings based on boron nitride, which are highly effective against microbial pathogens (up to 99.99%). They can become a safe alternative to the usual antibiotics in implantology since they do not have typical negative side effects. The results of the work are published in the international scientific journal ACS Applied Materials & Interfaces.

Nowadays, due to the significant increase in the number of surgical procedures around the world, scientists are solving the problem of microbial infections caused by implants. It is especially serious during orthopedic and dental operations. It is no secret that concomitant drug therapy for inflammation around implants often leads to side effects due to the characteristic properties of the antibiotics, as well as its high doses.

A group of young scientists from NUST MISIS has proposed a non-standard solution to the problem by investigating the interaction of antibiotic-resistant gram-negative bacteria Escherichia coli (E.coli) and a nanofilm consisting of a structured boron nitride surface. It turned out that such a coating inactivates 100% of bacterial cells after 24 hours.

“Hexagonal boron nitride has a complex of unique physicochemical and mechanical properties. As a result of the experiments, we have found out that the special specific structure of boron nitride nanoparticles provides a bactericidal effect comparable to that of an antibiotic: bacteria die as a result of direct physical contact with a special needle-shaped surface of the nano-film. At the same time, there are no side effects typical of an antibiotic on the tissues of the body, and boron nitride itself does not cause cytotoxicity,” said Christina Gudz, co-author of the study, a researcher at the NUST MISIS Inorganic Nanomaterials Laboratory.

The researchers went further and filled the micro-pores of a thin coating of boron nitride with the gentamicin antibiotic. The result is an antibacterial effect due to the complete release of the drug in a short initial period. Moreover, its dose was an order of magnitude less than with a conventional injection.

“Taking into account an average patient weight of 60 kg, his daily antibiotic dose is approximately 180 mg; provided that the implant area is, say, 30 cm2 and given that 55 μg of antibiotic is released from the nano-coating under study on the first day, it turns out that the proposed method assumes 100 times less antibiotic than with a standard injection,” added Christina Gudz.

According to the authors of the development, the application of an antibacterial film based on boron nitride nanoparticles to the implant can minimize the risk of bacterial contamination due to the physical properties of the surface itself, as well as, in the case of antibiotic modification, local delivery of a minimum amount of the bactericidal component without weighting the implant.

At present, the team is completing in vitro studies of the obtained coatings and is also working on optimizing the coating method for its future use.

###

Media Contact
Lyudmila Dozhdikova
[email protected]

Original Source

https://en.misis.ru/university/news/science/2020-09/6922/

Related Journal Article

http://dx.doi.org/10.1021/acsami.0c10169

Tags: Biomedical/Environmental/Chemical EngineeringCritical Care/Emergency MedicineDentistry/Periodontal DiseaseDermatologyMedicine/HealthOrthopedic MedicineResearch/DevelopmentSurgeryTransplantationTrauma/Injury
Share12Tweet8Share2ShareShareShare2

Related Posts

Unraveling Apolipoprotein A-IV in Cardiac Amyloidosis

October 20, 2025

Digital Self-Service Platform Enhances Lung Cancer Screening Uptake

October 20, 2025

Parity and Lactation Trigger T Cell Breast Cancer Protection

October 20, 2025

Nurses’ Views on AI: Benefits, Challenges, Ethics

October 20, 2025
Please login to join discussion

POPULAR NEWS

  • Sperm MicroRNAs: Crucial Mediators of Paternal Exercise Capacity Transmission

    1267 shares
    Share 506 Tweet 316
  • Stinkbug Leg Organ Hosts Symbiotic Fungi That Protect Eggs from Parasitic Wasps

    300 shares
    Share 120 Tweet 75
  • New Study Suggests ALS and MS May Stem from Common Environmental Factor

    128 shares
    Share 51 Tweet 32
  • New Study Indicates Children’s Risk of Long COVID Could Double Following a Second Infection – The Lancet Infectious Diseases

    103 shares
    Share 41 Tweet 26

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

Blood Test Advances Personalized Immunotherapy for Muscle-Invasive Bladder Cancer After Surgery

Unraveling Apolipoprotein A-IV in Cardiac Amyloidosis

Karel Svoboda and Jay Shendure Elected to National Academy of Medicine

Subscribe to Blog via Email

Enter your email address to subscribe to this blog and receive notifications of new posts by email.

Join 65 other subscribers
  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.