Single-port one-anastomosis transit bipartition appears technically feasible and achieved favorable perioperative safety along with encouraging short-term weight-loss and cosmetic results in a retrospective single-center case series of 16 patients.
One-anastomosis transit bipartition has emerged as a metabolic surgical procedure designed to combine functional restriction and diversion mechanisms while maintaining endoscopic access to the remnant stomach.
Although growing clinical interest in minimally invasive techniques has spurred the adoption of single-port laparoscopy in bariatric surgery, reports documenting the feasibility of performing one-anastomosis transit bipartition through a single-port approach have remained rare.
To investigate the viability of this surgical strategy, researchers analyzed records from 16 consecutive patients who underwent single-port one-anastomosis transit bipartition between February 2024 and January 2026 at a single institution, with all operations carried out by the same surgical team.
The investigators compiled baseline demographic and metabolic records for the cohort, evaluating patient progress through postoperative assessments of weight reduction, metabolic indicators, perioperative safety outcomes, and cosmetic satisfaction measured with the Scar Cosmesis Assessment and Rating scale.
Among participants with available follow-up information, the procedure produced substantial weight reduction at 12 months, with patients recording a mean total weight loss of 33.07 percent and a mean excess weight loss of 90.21 percent.
Patients also demonstrated improvements across several key metabolic parameters during the follow-up period, specifically including reductions in fasting plasma glucose and glycated hemoglobin levels, while the surgical series recorded no major postoperative complications, reoperations, or hospital readmissions.
Early cosmetic evaluations conducted at the one-month postoperative milestone yielded a mean Scar Cosmesis Assessment and Rating score of 4.2 ± 3.4 among the 14 patients assessed, leading the authors to emphasize that while initial findings are promising, larger prospective studies with extended follow-up will be necessary to confirm the efficacy and reproducibility of the single-port approach.
The retrospective investigation was structured around clinical records from sixteen consecutive surgical patients who received single-port one-anastomosis transit bipartition between February 2024 and January 2026. To minimize variability in procedural execution, all operative interventions were completed by the same surgical team at a single institution. Researchers tracked baseline demographic data alongside initial metabolic indicators to establish a reference point for subsequent postoperative evaluations. In assessing the initial feasibility of this operative approach, the investigators focused on perioperative safety parameters, documented recovery milestones, and monitored patient progress across defined clinical follow-up intervals.
Metabolic and anatomical considerations formed the core rationale for evaluating this surgical strategy. As an operative technique, one-anastomosis transit bipartition combines functional restriction with digestive diversion mechanisms, maintaining an anatomical arrangement that preserves direct endoscopic access to the remnant stomach. While interest across the bariatric field has increasingly shifted toward minimally invasive laparoscopic modalities, single-port execution of this specific procedure has seen limited documentation. The current case series sought to address that evidentiary gap by recording whether the single-port configuration could be carried out successfully without introducing prohibitive operative obstacles or elevated perioperative hazards.
Follow-up evaluations tracked both metabolic responses and procedural recovery over distinct observation windows. Among individuals with complete twelve-month documentation, the authors reported a mean total weight loss of 33.07 percent, alongside a mean excess weight loss of 90.21 percent. In parallel with weight reduction, post-intervention testing indicated consistent improvements across primary glycemic markers, including fasting plasma glucose concentrations and glycated hemoglobin measurements. From a procedural safety standpoint, the cohort experienced an absence of major postoperative complications, with no instances requiring secondary surgical reoperation or unplanned hospital readmission during the monitored timeframe.
Cosmetic outcomes and surgical scarring were examined separately at one month following surgery using the Scar Cosmesis Assessment and Rating scale. Across the fourteen patients available for this specific cosmetic assessment, the mean recorded rating was 4.2 with a standard deviation of 3.4. While these short-term observations indicate encouraging technical feasibility and favorable early safety in selected candidates, the authors emphasized the inherent constraints of a single-center retrospective series. Confirming the broader clinical efficacy, long-term durability, and surgical reproducibility of single-port one-anastomosis transit bipartition will require larger, multi-patient prospective trials monitored over extended follow-up periods.
Subject of Research: Feasibility and short-term clinical outcomes of single-port one-anastomosis transit bipartition
Article Title: Early experience and short-term outcomes of single-port one-anastomosis transit bipartition: a single-center case series
Article References: Xu, F., Lu, B., Yang, D., Dong, W., Ma, H., & Yang, J. (2026). Early experience and short-term outcomes of single-port one-anastomosis transit bipartition: a single-center case series. BMC Surgery. https://doi.org/10.1186/s12893-026-04279-z
Image Credits: AI Generated
DOI: 10.1186/s12893-026-04279-z
Keywords: single-port laparoscopy, one-anastomosis transit bipartition, SP-OATB, metabolic surgery, bariatric surgery, weight loss outcomes, total weight loss, excess weight loss, fasting plasma glucose, HbA1c, Scar Cosmesis Assessment and Rating, SCAR scale, perioperative outcomes, minimally invasive surgery, remnant stomach, functional restriction, transit bipartition, retrospective case series
News Source: Ophelia Keating. (November 13, 2026). Single-Port One-Anastomosis Transit Bipartition Shows Favorable Short-Term Outcomes in Case Series. Scienmag.
