Cancer research using mini-organs from tumors and healthy tissue

Hans Clevers (Hubrecht Institute) and David Tuveson (Cold Spring Harbor Laboratory), experts in the field of stem cells and organoids, have written a review that summarizes the use of organoids in cancer research and shines a light on prospects for the future. These mini-organs can be used to study tumor biology, model tumor development, and to test existing and new therapies in a patient specific way. The main points of the review are explained by Hans Clevers in the attached video. The review was published in the scientific journal Science, on the 6th of June.

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Publication

Cancer modeling meets human organoid technology. David Tuveson and Hans Clevers. Science 2019.

Hans Clevers is group leader at the Hubrecht Institute, professor of Molecular Genetics at the UMC Utrecht and Utrecht University, Research Director of the Princess Máxima Center for Pediatric Oncology and Oncode Investigator.

About the Hubrecht Institute

The Hubrecht Institute is a research institute focused on developmental and stem cell biology. It encompasses 24 research groups that perform fundamental and multidisciplinary research, both in healthy systems and disease models. The Hubrecht Institute is a research institute of the Royal Netherlands Academy of Arts and Sciences (KNAW), situated on the Utrecht Science Park. Since 2008, the institute is affiliated with the UMC Utrecht, advancing the translation of research to the clinic. The Hubrecht Institute has a partnership with the European Molecular Biology Laboratory (EMBL). For more information, visit http://www.hubrecht.eu.

Note for the press

For more information, please contact Melanie Fremery, the communications officer of the Hubrecht Institute: [email protected] or 0031658911260 (between during 9:00AM and 6:00PM Dutch time).