• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
Wednesday, August 6, 2025
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Health

Towards more efficient catalysts

Bioengineer by Bioengineer
February 16, 2024
in Health
Reading Time: 4 mins read
0
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

Researchers from the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS), Harvard Department of Chemistry & Chemical Biology, and Utrecht University have reported on a previously elusive way to improve the selectivity of catalytic reactions, adding a new method of increasing the efficacy of catalysts for a potentially wide range of applications in various industries including pharmaceuticals, cosmetics and much more. 

Towards more efficient catalysts

Credit: Harvard SEAS

Researchers from the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS), Harvard Department of Chemistry & Chemical Biology, and Utrecht University have reported on a previously elusive way to improve the selectivity of catalytic reactions, adding a new method of increasing the efficacy of catalysts for a potentially wide range of applications in various industries including pharmaceuticals, cosmetics and much more. 

The research is published in Nature Catalysis. 

The chemical industry relies on catalysts for over 90 percent of its processes and nearly all these catalysts consist of nanoparticles dispersed on top of a substrate. Researchers have long suspected that the size of individual nanoparticles and the distance between them play important roles in the speed of, and the products produced in the catalytic reaction, but because nanoparticles are prone to moving around and agglomerating during catalysis, it’s been difficult to study exactly how. 

Over the past decade, Joanna Aizenberg, the Amy Smith Berylson Professor of Materials Science and Professor of Chemistry & Chemical Biology, and her lab have been drawing inspiration from nature to build highly ordered, porous materials for a wide range of catalytic reactions. Inspired by the structure of butterfly wings, the researchers designed a new catalyst platform that partially embeds nanoparticles into the substrate, trapping them so they don’t move around during catalysis, while leaving the rest of the nanoparticles’ surface exposed, enabling them to perform the catalytic reactions efficiently and without agglomeration. 

The researchers found that the distance between particles had a huge impact on the selectivity of the reaction. 

“Many industrially-relevant chemical reactions follow a cascade whereby chemical A is turned to chemical B which can then be turned into chemical C and so forth,” said Kang Rui Garrick Lim, a graduate student in the Aizenberg Lab and first author of the study. “In some catalytic processes, the intermediate chemical, chemical B, is the goal, while in others it is the end product, chemical C. The selectivity of the catalyst refers to whether it favors the production of chemical B or chemical C.”

A good example of this is the production of benzyl alcohol, a chemical used in everything from shellacks, paints, and leather production to intravenous medications, cosmetics, and topical drugs.

Benzyl alcohol is the intermediate chemical B, derived from the hydrogenation of benzaldehyde (chemical A), before the reaction creates toluene (chemical C), another commonly used chemical but of lower value. In order to produce benzyl alcohol efficiently, the formation of toluene needs to be suppressed.

Currently, to make the more useful benzyl alcohol, the catalytic hydrogenation reaction is slowed down, or not run to completion, to ensure that the reaction will stop at B and form as little toluene as possible. 

“Generally, to make these intermediate chemicals, you make the catalyst less reactive and the overall reaction slower, which is not productive at all,” said Lim. “Catalysts are meant to speed things up, not slow them down.”

The researchers demonstrated their platform in the catalytic formation of benzyl alcohol. Lim and the team found that when catalytic metal nanoparticles were placed further apart on the substrate, the reaction was more selective towards benzyl alcohol, the intermediate chemical. When the nanoparticles were closer together, the reaction was more selective towards toluene, the end product. Given that the distance between nanoparticles can be adjusted synthetically using the bioinspired catalyst platform, the research suggests that the same catalyst platform can be easily adapted for a range of intermediate or end product chemicals. 

“Catalysis is central to production of a whole range of extremely important materials that are used in pharmaceuticals, consumer products and in manufacturing many products all of us use in everyday life,” said Aizenberg. “Adding this selectivity-improving tool to the chemist’s arsenal is extremely important. It will allow more effective tuning of catalytic processes, more economical use of the feedstocks accompanied by the reduction of energy consumption and waste generation.  We hope that chemists will use our platform in further optimization of new and existing catalytic processes.”

Next, the team will use the same platform to understand how the size of nanoparticles impacts the reaction at fixed distances between nanoparticles.

Harvard’s Office of Technology Development has protected the intellectual property out of Professor Aizenberg’s lab, which is the underlying technology of this research.

The research was co-authored by Selina K. Kaiser, Haichao Wu, Sadhya Garg,

Marta Perxes Perich, Jessi E. S. van der Hoeven and Michael Aizenberg. It was supported in part by the Integrated Mesoscale Architectures for Sustainable Catalysis (IMASC), an Energy Frontier Research Center funded by the US Department of Energy, Office of Science, Basic Energy Sciences under award number DE-SC0012573 and by the US Defense Threat Reduction Agency (DTRA) under award number HDTR1211001612.



Journal

Nature Catalysis

DOI

10.1038/s41929-023-01104-1

Share12Tweet8Share2ShareShareShare2

Related Posts

Childhood Verbal Abuse Has Comparable Effects on Adult Mental Health as Physical Abuse, Study Finds

Childhood Verbal Abuse Has Comparable Effects on Adult Mental Health as Physical Abuse, Study Finds

August 6, 2025
Msx2 Inhibits Osteoclast Fusion, Boosts Bone Growth

Msx2 Inhibits Osteoclast Fusion, Boosts Bone Growth

August 6, 2025

Three-Step Forensic Method Differentiates Human, Pig Nails

August 6, 2025

Decoding Gaming Disorder: Insights from Network Analysis

August 6, 2025

POPULAR NEWS

  • blank

    Neuropsychiatric Risks Linked to COVID-19 Revealed

    74 shares
    Share 30 Tweet 19
  • Overlooked Dangers: Debunking Common Myths About Skin Cancer Risk in the U.S.

    61 shares
    Share 24 Tweet 15
  • Predicting Colorectal Cancer Using Lifestyle Factors

    46 shares
    Share 18 Tweet 12
  • Dr. Miriam Merad Honored with French Knighthood for Groundbreaking Contributions to Science and Medicine

    47 shares
    Share 19 Tweet 12

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

Exploring Ceramics: Phase, Conductivity, and Thermistor Insights

Childhood Verbal Abuse Has Comparable Effects on Adult Mental Health as Physical Abuse, Study Finds

Breaking Barriers: New Checkpoint Targets Empower NK Cells to Transform Cancer Immunotherapy

  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.