• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
Sunday, October 26, 2025
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Health

The fate of drug discovery in academia; dumping in the publication landfill?

Bioengineer by Bioengineer
February 5, 2024
in Health
Reading Time: 3 mins read
0
Figure 1
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

“[…] fruitful efforts to bring more drugs from bench to bedside could only be possible if we do not leave them ‘midway’!”

Figure 1

Credit: 2024 Saqib et al.

“[…] fruitful efforts to bring more drugs from bench to bedside could only be possible if we do not leave them ‘midway’!”

BUFFALO, NY- February 5, 2024 – A new editorial paper was published in Oncotarget’s Volume 15 on January 24, 2024, entitled, “The fate of drug discovery in academia; dumping in the publication landfill?”

In this new editorial, researchers Uzma Saqib, Isaac S. Demaree, Alexander G. Obukhov, Mirza S. Baig, Amiram Ariel, and Krishnan Hajela, from Devi Ahilya Vishwavidyalaya, Indore, discuss drug discovery—a tedious process that is time consuming in both divulging whether a molecule is efficacious and specific in hitting the target and also in confirming that the potential drug does not cause severe adverse effects. Many drug candidates fail crossing multiple checkpoints of this long journey; they lag in one or several aspects and never move beyond the research bench to contribute to public health. These setbacks make the process of drug discovery very time consuming, expensive, and tedious. 

“This viewpoint is focused on delineating how and why the multi-million [dollar] research efforts in the field of drug discovery often fail to reach its full potential.”

There is no shortage of studies focusing on drug discovery. They are published on a daily basis describing the efforts encompassing conventional and/or modern drug discovery technology, including structure-based drug design (SBDD), virtual screening, high-throughput screening (HTS), Artificial Intelligence (AI), and cell-based screening approaches (Figure 1). However, many drug development strategies are rather fuzzy in their advancement. 

Thus, there is a large gap between drug “discovery” and “development.” This part could be attributed to the lack of synergy between Academia and Industry at multiple levels. A significant part of this failure results from the lack of streamlining of drug development process. 

“In the current perspective, we discussed why many therapeutic molecules never make it to clinical studies despite being proven efficacious pre-clinically. Additionally, we discussed the possible solutions to overcome this défaut of the drug development process.”

 

Read the full paper: DOI: https://doi.org/10.18632/oncotarget.28552 

Correspondence to: Krishnan Hajela

Email: [email protected] 

Keywords: drug discovery and development, clinical trials, academia-industry collaboration, translational research, drug database

Click here to sign up for free Altmetric alerts about this article.
 

About Oncotarget: Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science.

To learn more about Oncotarget, visit Oncotarget.com and connect with us on social media:

  • X, formerly Twitter
  • Facebook
  • YouTube
  • Instagram
  • LinkedIn
  • Pinterest
  • Reddit
  • Spotify, and available wherever you listen to podcasts

 

Click here to subscribe to Oncotarget publication updates.

For media inquiries, please contact [email protected].

 

Oncotarget Journal Office

6666 East Quaker Street., Suite 1A

Orchard Park, NY 14127

Phone: 1-800-922-0957 (option 2)

###



Journal

Oncotarget

DOI

10.18632/oncotarget.28552

Method of Research

Commentary/editorial

Subject of Research

People

Article Title

The fate of drug discovery in academia; dumping in the publication landfill?

Article Publication Date

24-Jan-2024

Share12Tweet8Share2ShareShareShare2

Related Posts

Boosting Midwifery Skills with Virtual Reality Learning

October 26, 2025

Effective Neonatal Tetanus Treatment: A Nigerian Case Study

October 26, 2025

STK19 Enhances Cisplatin Efficacy in Tongue Cancer

October 26, 2025

Essential Differentiated Care Needed to Combat Tuberculosis

October 26, 2025

POPULAR NEWS

  • Sperm MicroRNAs: Crucial Mediators of Paternal Exercise Capacity Transmission

    1283 shares
    Share 512 Tweet 320
  • Stinkbug Leg Organ Hosts Symbiotic Fungi That Protect Eggs from Parasitic Wasps

    310 shares
    Share 124 Tweet 78
  • ESMO 2025: mRNA COVID Vaccines Enhance Efficacy of Cancer Immunotherapy

    195 shares
    Share 78 Tweet 49
  • New Study Suggests ALS and MS May Stem from Common Environmental Factor

    134 shares
    Share 54 Tweet 34

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

Boosting Midwifery Skills with Virtual Reality Learning

Goat Genome Study Uncovers Genes for Adaptation

Effective Neonatal Tetanus Treatment: A Nigerian Case Study

Subscribe to Blog via Email

Enter your email address to subscribe to this blog and receive notifications of new posts by email.

Join 67 other subscribers
  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.