PGK1 kinase activity disables a host chaperone to restrict multiple viruses
Experimental laboratory and mouse studies found that PGK1’s non-canonical kinase activity promotes degradation of a host chaperone needed by several ...
Tag: viral immune evasion
Pig-Killing Virus Unmasked: One Protein Quietly Disables Two Cellular Alarm Systems
New research shows the African swine fever virus protein QP509L suppresses innate immunity by simultaneously blocking STING trafficking and STAT1-dependent ...
Immune Checkpoint Modifications: Mechanisms and Therapeutic Potential
In recent years, the field of cancer immunotherapy has been revolutionized by an ever-deepening understanding of immune checkpoints. These molecular ...
Mucin-like Protein Drives Crimean-Congo Fever Virulence
In a groundbreaking development that could reshape the landscape of hemorrhagic fever research and vaccine development, scientists have uncovered the ...
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