Tag: therapeutic resistance

A review in Molecular Cancer examines how lactate and lysine lactylation regulate tumor biology, highlight challenges in establishing causality, and ...

A new computational framework identifies a fibroblast-driven epigenetic subtype of gastric cancer associated with therapeutic resistance and an immunosuppressive microenvironment.

A new review maps how the three secreted FGFBP proteins tune FGF signaling in physiology and act as divergent prognostic ...

A new open-access review describes how the m6A RNA modification acts as a key determinant in reshaping the tumor microenvironment ...

A new review in the Journal of Translational Medicine examines how cancer stem cells, vascularization and immune evasion contribute to ...

A Molecular Cancer review redefines the MAD gene family as a unified HORMA-domain genome surveillance system linking spindle checkpoint control ...

A peer-reviewed review examines protein acylation as a link among cancer metabolism, tumor plasticity, therapeutic resistance and proposed biomarker-guided treatment ...

A 2026 collection of five reviews and one small tissue-expression study shows that autophagy can restrain or support solid tumors ...

A new review argues that the mitochondrial peptide MOTS-c acts as a context-dependent stress signal with protective roles in metabolic ...

A new review identifies three fibroblast-driven mechanisms that make liver cancer cells resistant to kinase inhibitors and immunotherapy, while warning ...

A new review argues that host chromatin architecture and three-dimensional genome rewiring, not just HPV oncoproteins, stabilize malignant states and ...

A new review in Cancer Cell International details how cancer-associated fibroblasts remodel the colorectal tumor microenvironment and drive resistance to ...

Recent studies have illuminated the multifaceted role of cathepsin Z in prostate cancer, a topic that has sparked intense discussion ...