Tag: T Cells

A small exploratory German study found that antibody responses to influenza vaccination were broadly similar across BMI groups, while obese ...

A single-cell reanalysis of public datasets identifies an SPP1-expressing macrophage subset in breast cancer bone metastases and predicts its signaling ...

High-dimensional immune profiling of 104 trial participants shows interferon-gamma restored monocyte function but did not prevent ventilator-associated pneumonia, pointing instead ...

New research shows the immune protein perforin can kill tumor cells on its own by triggering iron-dependent ferroptosis, even when ...

Genetic screens in aged mice identify Dusp5 and Zfp219 as regulators whose deletion can restore anti-tumor T cell function, with ...

A prospective Swedish study found that a low pre-transplant CD4/CD8 ratio combined with cytomegalovirus seropositivity was associated with later BK ...

A mouse study in The Journal of Immunology reports that hyperglycemia reprograms T cells through an IGF1-IGF1R signaling pathway to ...

New research in Nature finds that 33 of 34 lupus patients carried neutrophils with RNA splicing mutations producing neoantigens that ...

A six-gene T cell-derived signature built from single-cell transcriptomics stratified hepatocellular carcinoma patients by survival risk in two independent cohorts.

A new study links exercise-responsive genes, including JUNB, to T-cell state changes and cardiac transcriptional responses in type 2 diabetes.

A cross-sectional digital pathology study of 154 gastric biopsies found that neutrophilic infiltration and lymphoid follicles were significantly associated with ...

A vitamin B5 derivative called pantethine suppressed dendritic cell hyperactivation, prevented psoriasis in mice and improved symptoms in a small ...

A case-based analysis reports case-specific lymphocyte and activation marker changes in two young children with recurrent infections after a short ...

A Dana-Farber-led Immunity study shows that p53-mutant cancers can evade T-cell detection through several mechanisms, while laboratory ERAP1 inhibition restores ...

An interpretable deep learning model called SPACER reads spatial transcriptomics data to reveal the molecular and spatial rules that govern ...

A large Chinese cohort study shows that lymphocyte subsets in women undergo a pronounced reconfiguration around menopause, with B cell ...

A new study combines Mendelian randomization with mouse experiments to link specific gut bacteria, including Parabacteroides goldsteinii and Alistipes shahii, ...

Wistar Institute researchers found that the neurotransmitter neuromedin U suppresses T cell infiltration at the earliest stage of neuroendocrine prostate ...

A single-cell RNA sequencing atlas of biliary atresia livers reveals expanded pro-inflammatory neutrophil subsets, activated cytotoxic lymphocytes, and injured endothelial ...

New research shows CD4+ T cells kill the progenitor cells needed to rebuild bone after injury, while regulatory T cells ...