Same Drug, Different Cells: Why mTOR Inhibition in Plaques Defies Simple Rules
A new review argues that mTOR's effects in atherosclerotic plaques depend on cell state, plaque niche, signalling complex and drug ...
Tag: Smooth muscle cells
Tacrolimus Eases Fibrosis-Linked Pulmonary Hypertension in Rats by Targeting Vascular Remodeling
A rat study finds that low-dose tacrolimus lowered right ventricular pressure and reduced pulmonary vascular remodeling through endothelial protection and ...
Smooth Muscle Cells Take Center Stage as Gene Study Reveals New Clues to Pulmonary Hypertension
By merging bulk and single-cell RNA sequencing with machine learning and lab experiments, researchers have identified smooth muscle cells as ...
RSAD2-YTHDF1 Axis Drives IBD via Mitochondria
In a groundbreaking study recently published in Nature Communications, researchers have unveiled a novel molecular pathway implicating the RSAD2-YTHDF1 axis ...
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Vaping adults without smoking history report slightly more respiratory symptoms, large survey finds
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AI Advances in Upper Limb Prosthetics Reviewed
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Deep Learning Model Accelerates Drug Target Screening and Repurposing Opportunities