Tag: SARS-CoV-2

A review in EMBO Reports argues that viruses trigger autoimmunity through shared mechanisms that erode B-cell tolerance, with the anatomical ...

A mouse study finds that priming with an intramuscular mRNA vaccine before an intranasal adjuvanted booster, through a type I ...

A country-level study in BMC Public Health found that mandatory folic acid food fortification was associated with roughly 70 percent ...

A large RECOVER Initiative study found Paxlovid treatment within five days of infection was associated with reduced Long COVID risk ...

A new study reports that the SARS-CoV-2 spike protein competitively inhibits plasmin-mediated cleavage of the epithelial sodium channel ENaC at ...

A Japanese case report describes a 17-year-old student who was bedridden for much of the day after SARS-CoV-2 infection and, ...

A computational study generated nearly 16,000 nirmatrelvir analogues and a similarity-based binding score to prioritize candidate inhibitors of the MERS-CoV ...

A new review evaluates how short synthetic nucleic acid molecules called aptamers could improve diagnosis and treatment of viral and ...

A survey of 1,157 UK adults found 92 percent support wastewater-based epidemiology, but comfort drops sharply for household-level monitoring and ...

A new framework ranks viral k-mers by combining strain-distinguishing power with mutation impact and protein annotation information.

Two new PLOS Biology studies link broad ACE2 receptor use in bat sarbecoviruses to shared spike epitopes that human antibodies ...

People with hematologic diseases such as leukemia, myelodysplastic syndrome and aplastic anemia face a well-documented vulnerability to COVID-19, driven by ...

A new review highlights the JAK/STAT signalling pathway as a potential link between SARS-CoV-2 infection, post-COVID autoimmune phenomena and the ...

A systematic review and meta-analysis confirms that hydroxychloroquine, chloroquine, ivermectin, azithromycin and doxycycline lack clinically meaningful efficacy against COVID-19, and ...

A serosurvey of 20,748 people in Burkina Faso, Ghana and Nigeria found SARS-CoV-2 IgG seropositivity ranging from 24.1 to 76.4 ...

Cryo-EM and functional assays show that the JN.4-specific A475V substitution remodels the SARS-CoV-2 RBD large loop and reduces ACE2-binding affinity ...

A study in BMC Infectious Diseases reports that periodontal inflammation is associated with elevated activity of phosphatidylserine-dependent, TIM-mediated entry pathways ...

A laboratory study of pediatric and adult liver organoids found higher Omicron viral RNA accumulation and a stronger innate immune ...

A 2023 pilot across 112 community health care sites in the Democratic Republic of the Congo found that 4.9% of ...

A retrospective single-center cohort of 4,173 hospitalized Omicron BA.2 cases found that 934 patients had hypertension, with most experiencing mild ...