Aging-like B cells emerge as hidden drivers of rheumatoid arthritis onset
Single-cell multiomics reveals that people who progress from ACPA-positive at-risk status to clinical rheumatoid arthritis carry an expansion of senescent-like ...
Tag: Rheumatoid arthritis
Alopecia Areata Study Reveals Sharp Racial Divides in Immune Disease Risk
A large retrospective cohort study using U.S. health record data finds that Black and white patients with alopecia areata face ...
Ancient Ayurvedic Formula Triphalaguggul Shows Potent Anti-Arthritis Action in Rat Study
A traditional Ayurvedic formulation called Triphalaguggul dramatically reduced inflammation and cartilage damage in rat models of osteoarthritis and rheumatoid arthritis ...
Scientists Identify HERC4 as the Molecular Switch That Turns TNF Survival Signals Into Cell Death
Researchers have discovered that the protein HERC4 acts as the critical molecular switch that converts TNF survival signalling into cell ...
Cell-Mimicking Nanoparticles Earn UC San Diego Engineer MacArthur Genius Grant
UC San Diego nanoengineer Liangfang Zhang has won a 2026 MacArthur Fellowship for his pioneering cell-mimicking nanoparticles that camouflage drugs, ...
Simple Blood Score Reveals Hidden Nutritional Threshold in Rheumatoid Arthritis Activity
A study of 984 rheumatoid arthritis patients finds that the Prognostic Nutritional Index, a simple blood-based score combining albumin and ...
AI Method Reads Tissue Fingerprints to Find Disease Hotspots Earlier
A new deep-learning method called VIMA converts tissue patches into numerical fingerprints and uses rigorous statistics to uncover disease-associated spatial ...
Methotrexate Blunts Neutrophil Migration and Boosts LOX-1 Expression, Study Finds
New research shows methotrexate selectively impairs neutrophil chemotaxis while increasing LOX-1 expression, leaving other key neutrophil functions untouched.
How a Single Amino Acid Pathway May Steer Autoimmune Disease
A new review in the Journal of Translational Medicine details how the glutamine-glutamate metabolic axis regulates immune cell fate and ...
Infrared Light and Metabolomics Point Toward a Faster Fibromyalgia Test
An exploratory study combining infrared spectroscopy with mass spectrometry metabolomics shows that fibromyalgia leaves detectable molecular traces in blood, opening ...
Castor Plant Chemistry Shows Surprising Anti-Inflammatory Power in Lab Tests
A new study combines LC-MS profiling, protein denaturation assays, and molecular dynamics simulations to reveal that castor plant formulations contain ...
AI Chatbots Answer Thousands of Rheumatology Patient Questions in Landmark Real-World Test
A nationwide German study deployed ten guideline-grounded AI chatbots across rheumatology centres, recording over 6,000 patient questions and finding that ...
Histone Lactylation Drives Rheumatoid Arthritis via NFATc2
In a groundbreaking study recently published in Nature Communications, researchers have unveiled a novel molecular mechanism that exacerbates rheumatoid arthritis ...
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