Review Highlights Epigenetic and Metabolic Remodeling in Pulmonary Arterial Hypertension
A scientific review details how disrupted metabolic pathways regulate epigenetic remodeling in pulmonary vascular cells during pulmonary arterial hypertension.
Tag: Pulmonary arterial hypertension
Care dependency and associated clinical factors in patients with pulmonary hypertension: a cross-sectional study
A cross-sectional study of 85 outpatients found that symptom severity, functional class, and diabetes independently predict care dependency in pulmonary ...
Echocardiography Guideline Shifts Significantly Alter Right Ventricular Measurements and Enlargement Diagnoses
A comparative echocardiographic analysis reveals that revised 2025 guideline definitions substantially reduce right ventricular transverse diameter measurements and generate prominent ...
First Nationwide Look at Sotatercept Use in France Finds 257 Patients Treated Under Early Access
A nationwide French cohort study describes the first 257 patients treated with sotatercept for pulmonary arterial hypertension since its June ...
Cutting a Neck Nerve Rewires Gene Networks to Ease Rat Lung Hypertension
In a rat model of pulmonary arterial hypertension, surgically cutting the cervical sympathetic trunk lowered lung pressures and reshaped transcription ...
Two decades of PAH stem cell research mapped, revealing a shift toward cell-free therapies
A bibliometric analysis of 891 publications from 2006 to 2026 maps how pulmonary arterial hypertension research shifted from endothelial progenitor ...
Infant cobalamin C deficiency linked to severe vascular complications
A Chinese infant with genetically confirmed cobalamin C deficiency developed rare, life-threatening vascular complications that resolved rapidly with combined metabolic ...
Sotatercept May Reach Beyond Pulmonary Hypertension Into Heart Failure and Transplant Care
An opinion article argues that the activin-trap drug sotatercept, proven in pulmonary arterial hypertension and supported by the CADENCE trial ...
Damaged Mitochondrial DNA Emerges as a Central Driver of Pulmonary Arterial Hypertension
A new review argues that oxidized mitochondrial DNA acts as both a persistent inflammatory signal and a potential biomarker driving ...
Long Drives to Rare Disease Care Reveal Who Is Sickest in Italy
A large Italian registry study finds that patients with systemic sclerosis who travel farther for tertiary care have more severe ...
Three Heart Measurements on a Routine CT Scan Could Reveal Hidden Lung Hypertension
Researchers in China have developed a nomogram based on three CTPA-derived cardiac measurements that identifies group 1 pulmonary arterial hypertension ...
One Pill, Two Drugs: How a Single-Tablet PAH Therapy Is Reshaping US Practice
A new real-world study of 144 US patients shows the first once-daily single-tablet macitentan/tadalafil combination for pulmonary arterial hypertension is ...
Hidden Gatekeeper Protein Decides Which Vessel Signals Endothelial Cells Hear
Fluorescent live-cell reporters reveal that the protein FKBP12 acts as a gatekeeper deciding which TGF-β superfamily ligands activate SMAD signaling ...
Endothelin Receptor Antagonists for Pulmonary Hypertension Treatment
In the realm of pulmonary arterial hypertension (PAH), a group of severe and often fatal disorders characterized by elevated blood ...
POPULAR NEWS
-
Coconut Rhinoceros Beetle Larval Frass Enhances Plant Growth as Direct Fertilizer
-
Affective and Emotion Terms Reflect Divergent AI Education Research Orientations
-
Bifidobacterium Enzyme PNGaseA Unlocks Specialized Breast Milk Sugars in Infants
-
HIPEC Treatment Proxy Shows Limited Incremental Prognostic Value in Appendiceal Cancer