Tag: precision oncology

A multicenter study found that FH-deficient kidney cancer patients with DNA damage repair gene mutations showed significantly higher response rates ...

A review in Cellular Oncology proposes that tumor blood vessels actively regulate antitumor immunity through angiocrine, metabolic and structural mechanisms.

A conference synthesis report in BMC Proceedings outlines African priorities for precision oncology, from genomic infrastructure and cancer registries to ...

A new review in Clinical and Experimental Medicine examines how molecular dynamics, docking, machine learning and AI platforms are being ...

A ten-year bibliometric analysis of 320 articles finds artificial intelligence research on triple negative breast cancer peaked at 104 publications ...

A retrospective US cohort of 2,694 pancreatic cancer patients found MTAP deletion in 30.5 percent of tumors and consistently lower ...

A new review examines how patient-derived tumor organoids retaining immune cells could improve preclinical prediction of immunotherapy response while noting ...

A newly published consensus standard defines unified workflows, validation criteria and drug testing protocols for breast cancer organoids grown from ...

A Moroccan cohort study of 215 advanced ovarian cancer patients found local HRD testing feasible, with 55.1 percent of evaluable ...

A new computational framework combines protein interaction network topology with imbalance-aware ensemble machine learning to identify cancer driver genes, achieving ...

A retrospective study of 125 advanced sarcoma patients found molecular tumor board recommendations led to treatment in 32.8 percent, with ...

A Nature Reviews Cancer review argues that theranostics should expand beyond radiolabelled peptides to include nanotheranostics, microtheranostics and imaging-guided surgery.

A microfluidic platform called GradientScreen generates overlapping drug gradients and its combination response metrics correlate with minimal residual disease and ...

A new review details how the pan-RAS inhibitor daraxonrasib doubled overall survival in a phase III pancreatic cancer trial and ...

A new open-access review maps how stem cell-derived extracellular vesicles could serve as dual therapeutic and diagnostic tools in precision ...

A systematic analytical review maps how ultra-sensitive biosensors and programmable nanorobotic platforms are being combined into closed-loop cancer theranostic systems, ...

A review in Discover Oncology describes how the gut microbiota can modulate chemotherapy efficacy and resistance through drug sequestration, metabolic ...

A new study shows that the choice between Wnt-based and OncoPro culture medium reshapes the transcriptional state and drug sensitivity ...

A case report documents 35 months of oral ivosidenib therapy with partial remission and no adverse events in a man ...

A prospective trial found constitutional pathogenic variants in about 10 percent of solid tumor patients screened through comprehensive cancer genome ...