Tag: polygenic scores

A new PLOS Genetics study derives a corrected liability-scale conversion for covariate-adjusted binary GWAS that accounts for variation in disease ...

A study of 14,346 Native Hawaiians shows that combining trans-ancestry polygenic scores with machine-learning dietary scores substantially improves BMI prediction, ...

A study of 3,223 UK parent-offspring trios finds that cognitive and non-cognitive education-related polygenic scores show different associations with children's ...

A new probabilistic study shows that re-identifying anonymized genomes from predicted traits achieves high precision only under unrealistically favorable assumptions, ...

An analysis of 879,461 adult genomes found approximately 4.3 million to 5.3 million small variants per person, alongside de novo ...

A new review synthesizes genetic and epigenetic evidence showing that endurance performance is a polygenic, dynamically regulated trait shaped by ...

Researchers statistically imputed fluid intelligence scores for hundreds of thousands of UK Biobank participants, reducing ascertainment bias and uncovering 26 ...

A landmark genome-wide study of nearly 600,000 individuals identifies 624 genetic signals for childhood adiposity, many of which act only ...

A large UK Biobank analysis shows that cross-sectional and longitudinal studies yield directionally consistent but systematically different estimates of age-varying ...

In a revolutionary leap toward personalized medicine, researchers have been delving into the intricate relationships between genetics and the development ...