Tag: polygenic risk scores

A new Frontiers in Genetics review argues that the NOIA model overcomes a key obstacle to unbiased gene mapping just ...

Whole-genome sequencing of 21 predominantly low-risk patients with bleomycin-induced pneumonitis identified biologically plausible candidate variants but no single unifying genetic ...

A new narrative review describes how 2026 lipid guidelines shift ASCVD prevention toward lifetime risk models, once-in-a-lifetime Lp(a) screening and ...

Stratifying schizophrenia patients by symptom profile revealed three subtypes with distinct genetic risk loci and polygenic risk score patterns.

A new framework recalibrates published polygenic risk scores to local biobank data, improving risk prediction for coronary artery disease, breast ...

A PLOS Medicine Perspective argues that cardiovascular risk prediction is advancing on two fronts, using blood-based protein signatures and other ...

A new method called PRIMA incorporates polygenic risk scores into propensity score matching to help disentangle causal disease relationships from ...

A University of Exeter-led survey of nearly one million whole genomes shows everyone carries millions of variants, including rare disease-linked ...

A Hospital de Amor biobank has collected nearly 40,000 blood samples from more than 4,000 Brazilians to develop cancer risk ...

A new integrative review synthesizes 31 human studies showing how transporter, enzyme and target gene variants shape individual responses to ...

A major new review argues that Africa's unmatched genetic diversity, combined with rising mental health needs and growing continental research ...

A large genomic study of children with cleft lip and/or palate finds that common genetic variants do not explain the ...

A new PLOS Genetics study shows that shared genetic susceptibility across cancers is modest genome-wide but becomes structured and biologically ...

Researchers have adapted a two-stage sparse regression method called uniLasso to the UK Biobank, producing polygenic risk scores that match ...

Researchers built proteomic risk scores from nearly 3,000 blood proteins that predict type 2 diabetes, hypertension, and hyperlipidemia years in ...

In a groundbreaking correction to their original study, Boura, I., Sait, S., Marinakis, N.M., and colleagues have refined their insights ...

In a groundbreaking study leveraging the power of genetic research, a team of researchers has delved into the relationship between ...

In a groundbreaking study published recently in Nature Communications, researchers have unveiled compelling evidence about the complex and context-dependent nature ...

In a groundbreaking study that pushes the frontiers of neurogenetics, researchers have unveiled the intricate polygenic architecture underlying the developing ...

In a groundbreaking advancement in the field of immunogenetics, researchers have unveiled a novel polygenic scoring approach that predicts individual ...