Study Links Estrogen and APOE to Brain Structure in Women
A study in Alzheimer's Research & Therapy finds that APOE genotype and estrogen levels are associated with sex-specific differences in ...
Tag: Plasma biomarkers
Plasma extracellular vesicle immunoassay maps immune checkpoint proteins in breast cancer
Researchers developed a multiplexed immunoassay that measures immune checkpoint proteins on the surface of plasma extracellular vesicles and found generally ...
Blood tau test rivals autopsy findings in predicting Alzheimer’s symptoms
A blood test for tau protein fragments predicted Alzheimer's cognitive symptoms nearly as accurately as autopsy-confirmed brain pathology in a ...
Brain-derived vesicle profiling opens non-invasive window on Alzheimer’s in Down syndrome
Ultrasensitive profiling of neuron- and astrocyte-derived vesicles from plasma reveals stage-linked protein signatures of neurodegeneration, inflammation and vascular stress across ...
Research report: Short-interval variability and test-retest reliability of Alzheimer’s disease plasma biomarkers in a clinically heterogenous cohort
A UCL study of 92 participants found core Alzheimer's plasma biomarkers showed high test-retest reliability over intervals from 30 minutes ...
Kenya study finds protein biomarkers poorly distinguish bacterial, viral childhood pneumonia
In the internal validation dataset, the full model achieved an area under the receiver operating characteristic curve, or AUC, of ...
Two Blood Proteins Could Let Doctors Stage Alzheimer’s Disease With a Simple Draw
A new Nature Communications study shows that plasma eMTBR-tau243 and p-tau205 rise during the later tau aggregation stage of Alzheimer's ...
Finger-prick blood test for Alzheimer’s biomarkers works for some proteins but fails on pTau217
A Johns Hopkins study of 192 patients shows two FDA-cleared capillary blood collection devices reliably measure NfL, GFAP and Aβ42/40 ...
Walking Patterns Reveal Alzheimer’s Risk Differently in Women and Men, Study Finds
A new study of 253 older adults finds that amyloid pathology alters gait and hippocampal structure in sex-specific ways during ...
AI Transformer Reads Raw Protein Fingerprints to Sort Cells and Spot Severe COVID-19
A transformer-based deep-learning pipeline called ProFormer classifies single-cell and plasma proteomes directly from raw mass-spectrometry fingerprints, outperforming CNNs and enabling ...
Blood Tests for Brain Aging Fail to Predict Physical Decline in Large Study of Older Adults
A two-year study of 506 older adults in the COSMOS cohort found that plasma biomarkers of neurodegeneration, including NT1, NfL, ...
Dietary Glycation Products Pile Up Unevenly Across Aging Organs, Mouse Study Shows
Targeted mass spectrometry in aged mice reveals that dietary carboxymethyllysine accumulates selectively in the kidney and ileum while blood markers ...
Blood Test Reveals Hidden Brain Injury After Mini-Strokes With Normal Scans
A new study shows that patients with transient ischemic attack and normal brain MRI have elevated blood levels of the ...
New Plasma Biomarkers for Hepatocellular Carcinoma Detection
Recent advancements in the realm of cancer diagnostics are unveiling promising avenues for the identification of hepatocellular carcinoma (HCC), particularly ...
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