Tag: PD-1

A novel intravenous STING agonist, BI 1703880, synergises with radiotherapy and checkpoint inhibitors to generate durable anti-tumour immunity in preclinical ...

A single-cell analysis of nearly half a million cells from pancreatic tumors reveals how evolving clones reshape their DNA to ...

A new review in Molecular Biology Reports maps how checkpoint inhibitors, engineered cell therapies, and emerging immunotherapies are transforming treatment ...

Researchers at Lund University have shown that precision-cut slices of bladder tumors keep their immune cells alive and functional for ...

A patient-level synthesis of 40 published cases shows that nivolumab-induced hypophysitis predominantly damages the pituitary's cortisol-regulating axis, responds well to ...

A preclinical study shows that combining KRASG12D inhibition with CTLA-4 blockade dismantles a TGF-beta-driven regulatory T cell shield, sensitizing KRAS-mutant ...

A phase II pilot trial found that a single fecal microbiota transplantation combined with atezolizumab and bevacizumab was safe and ...

Plasma-derived small extracellular vesicles from head and neck cancer patients suppress T-cell proliferation, trigger apoptosis, and rewire immune checkpoint expression ...

A matching-adjusted indirect comparison of two landmark trials suggests retifanlimab significantly prolongs progression-free survival compared with avelumab in metastatic Merkel ...

Lung cancer remains one of the leading causes of cancer-related deaths worldwide. Among its types, non-small cell lung cancer (NSCLC) ...