Tag: Ovarian cancer

Researchers using saturation genome editing across cell types found that mammary cells can buffer some BRCA1 mutations, helping distinguish high-risk ...

A multi-omics study associates bisphenol A with ovarian cancer chemoresistance via stromal remodeling, finding in vitro that conditioned medium from ...

Researchers have identified coordinated disruption of thyroid hormone transport and receptor localization in high-grade serous ovarian cancer, demonstrating that restoring ...

A retrospective cohort study in Ghana reveals that adolescents and young adults with malignant ovarian germ cell tumours face substantial ...

Researchers have synthesized a 1-aminopyridine-stabilized gold and reduced graphene oxide nanocomposite that enhances dispersibility and induces apoptotic cell death in ...

A structured review and institutional case series indicates that ovarian small-cell carcinoma of pulmonary type frequently presents at advanced stages ...

A narrative review synthesises the cellular mechanisms, genetic engineering approaches, preclinical models, and clinical translation barriers of oncolytic virotherapy across ...

A review indicates that exosome-mediated microRNA transfer regulates apoptotic signaling pathways and drives chemoresistance in ovarian cancer.

A global analysis across 185 countries evaluated lifetime incidence and mortality risks for cervical, ovarian, and endometrial cancers in 2022, ...

A leakage-aware machine learning ensemble combining K-Nearest Neighbors and AdaBoost achieved an accuracy of 0.7644 in predicting ovarian cancer risk ...

A case report in Discover Medicine identifies a rare BRCA2 frameshift variant in a Chinese family, providing segregation evidence that ...

A review in the Journal of Translational Medicine explores how iron metabolism links ovarian cancer resistance to immune dysfunction and ...

Hoag researchers identified a blood signal for STIC, a microscopic precursor to ovarian cancer, potentially enabling detection years before a ...

An economic evaluation of the PAOLA-1 trial finds that olaparib plus bevacizumab maintenance in HRD-positive ovarian cancer exceeds standard cost-effectiveness ...

A new computational workflow identifies TPI1 as a metabolic target in ovarian cancer, with experimental validation confirming its role in ...

A new study identifies midkine as a key mediator of cisplatin resistance in ovarian cancer, linking it to the PI3K/AKT ...

A preclinical study shows that pentagalloylglucose inhibits ovarian cancer cell growth and promotes senescence by targeting AKT2 for degradation.

Mechanistic research links distinct efflux transporters to specific PARP inhibitor resistance in ovarian cancer, though researchers caution that clinical application ...

Researchers found that circular RNA circUBR5 promotes ovarian cancer progression and angiogenesis in cell and animal models through a hypoxia-driven ...

A single-cell transcriptomics study reveals that conserved fallopian tube epithelial programs drive chemoresistance and treatment response heterogeneity in ovarian high-grade ...