ADP-ribose, an NAD+ catabolite, drives neuronal ferroptosis through ENT2 inhibition
A new Nature Chemical Biology study identifies the NAD+ catabolite ADP-ribose as an inducer of neuronal ferroptosis through inhibition of ...
Tag: nucleotide metabolism
Lung cancer rewires its metabolism into a dynamic, adaptive network
A new review argues that lung tumours run an integrated, adaptable metabolic network rather than isolated pathways, explaining growth under ...
Scientists Link a DNA-Building Enzyme to Fat Rewiring and Chemotherapy Failure in Pancreatic Cancer
A new study identifies RRM2 as a gene that connects nucleotide metabolism and SREBP1/FASN-driven lipid remodeling to gemcitabine resistance in ...
RNA-Seq Reveals Nucleotide Metabolism in Medulloblastoma
Recent advancements in cancer research have illuminated the complex nature of medulloblastoma, a malignant brain tumor primarily affecting children. In ...
