Elevated CD93 expression in advanced non-small cell lung cancer correlates with an immunosuppressive tumor microenvironment and reduced immunotherapy response.
A study in JNCCN found that broad-based genomic sequencing before treatment was associated with longer survival in patients with advanced ...
A structured review outlines requirements for testing whether adaptive cancer immunotherapy dosing preserves efficacy while reducing toxicity.
A retrospective study in advanced non-small cell lung cancer demonstrates that a dynamic functional-nutritional score tracking albumin, grip strength, gait ...
Researchers have validated a candidate reference measurement procedure using duplex droplet digital PCR to establish traceable quantification of MET gene ...
In a Phase 1b clinical trial, the targeted therapy firmonertinib demonstrated durable antitumor activity in patients with uncommon EGFR-mutated non-small ...
Researchers have developed molecular filler-enhanced DNA nanomachines that quantify circulating tumor DNA mutations directly from plasma without enzymatic amplification.
A novel two-stage coagulation method rapidly isolates intact mitochondria that restore metabolic function and overcome drug resistance in cell models.
A phase II trial in stage II to IIIB lung squamous cell carcinoma found that neoadjuvant camrelizumab combined with chemotherapy ...
A study of 158 non-small cell lung cancer tissue samples identified high tumor cell CD73 expression as an independent predictor ...
A study of advanced non-small cell lung cancer cohorts shows that concurrent TP53 and LRP1B mutations predict improved progression-free survival ...
A comprehensive review examines circulating tumor DNA across solid tumors, highlighting its prognostic accuracy in minimal residual disease alongside key ...
A multicenter study demonstrates that combining clinical variables with CT radiomics features enables machine learning models to accurately distinguish peripheral ...
A retrospective study of 182 brain metastasis patients found that receiving postoperative Gamma Knife radiosurgery within 14 days was associated ...
Physicians and researchers from Gustave Roussy are presenting clinical trial findings spanning breast, lung, gastrointestinal, and paediatric cancers at the ...
Researchers found that PI4K2A promotes non-small cell lung cancer cell migration by directing internalized c-MET to RAB14-positive recycling endosomes independently ...
Hyperthermia enhances anti-PD-L1 immunotherapy efficacy in preclinical non-small cell lung cancer models by upregulating PD-L1 expression through activation of the ...
Researchers identified the mitochondrial Complex I subunit NDUFA10 as an ATF3-activated driver of bioenergetics and Akt-mTOR signaling in non-small cell ...
Researchers have found that the breast cancer drug abemaciclib suppresses tumor growth and halts signaling in preclinical lung cancer models ...
A multicenter single-cell transcriptomic atlas of non-small-cell lung cancer identifies distinct malignant cell states and microenvironmental interactions that drive metastatic ...
