Tag: NLRP3 inflammasome

A population-based nested case-control study finds that circulating miR-335-5p is elevated in diagnosed diabetes but lower before onset, improves two ...

A heat-inactivated, probiotic-fermented tamarind pulp relieved constipation in mice by reshaping gut microbiota, boosting short-chain fatty acids and indole metabolites, ...

A new editorial in Pediatric Research argues that Kawasaki disease should serve as a prototypic model for understanding the spectrum ...

A new GeroScience review details how failing mitochondria act as both initiators and amplifiers of cellular senescence and the chronic ...

New research in PLOS Pathogens reveals that exercise drives a protective metabolite pathway that pushes the NLRP3 inflammasome into a ...

A new study in Aging Cell shows that time-restricted feeding delays vascular aging in mice by remodeling the gut microbiota ...

A new review argues that the evolutionarily conserved IRE1α/XBP1 stress-signaling pathway, which governs protein folding, inflammation and insulin action, offers ...

A new review details how bacteria and viruses hijack or block the mitochondrial quality-control pathway of mitophagy to survive, evade ...

A new review proposes a kinetics- and mechanism-informed framework for using lipopolysaccharide-induced neuroinflammation models to screen phytochemicals with greater rigour ...

Heat-killed Bifidobacterium animalis subsp. lactis BB-12 protected mice from indomethacin-induced gastric ulcers as effectively as live probiotics and better than ...

A six-month hypocaloric diet that cut body weight by about 10 percent significantly suppressed NLRP3 inflammasome priming, oxidative stress, and ...

A new review argues that Huntington's disease is driven by widespread disruptions of interconnected protein networks, pointing to hub proteins ...

New research shows the dietary amino acid l-arginine directly binds the NLRP3 inflammasome and blocks its assembly, easing inflammatory and ...

A Nature Metabolism commentary highlights new evidence that the amino acid l-arginine can inhibit activation of the NLRP3 inflammasome, raising ...

A major review argues that the newly renamed polyendocrine metabolic ovarian syndrome is a lifelong systems-level disease driven by hypothalamic, ...

New research shows that salvianolic acid B, a polyphenol from red sage, protects human heart muscle cells from high-glucose injury ...

In recent research published in the Journal of Translational Medicine, the implications of the urothelial Piezo1 channel in bladder outlet ...