Tag: monoclonal antibodies

A controlled human study of malaria-infected mosquito bites identified the first human monoclonal antibodies against the mosquito salivary protein SG1L3, ...

A new review outlines how monoclonal antibodies, including Fc-mediated effector functions, may address the lack of licensed therapies for Andes ...

An AI-driven target discovery framework ranked ADAM17 first for biliary tract cancer, and antibody-drug conjugates and CAR-T cells built against ...

Two new PLOS Biology studies link broad ACE2 receptor use in bat sarbecoviruses to shared spike epitopes that human antibodies ...

Two newly developed mouse–marmoset chimeric monoclonal antibodies enabled controlled T cell depletion in common marmosets, revealing KSHV lytic replication and ...

A mouse-brain study generated maps of monoclonal antibodies and more than 6,000 proteins across tissue sections, demonstrating a preclinical method ...

A Journal of Translational Medicine review outlines how mRNA-encoded antibodies, bispecific constructs, and transient CAR expression could overcome the manufacturing ...

A French Delphi study found that MRI evidence of high activity most consistently led neurologists to recommend early monoclonal high-efficacy ...

Monoclonal antibody therapy, led by dupilumab, is transforming the treatment of eosinophilic esophagitis in children after decades of limited options.

A comprehensive Molecular Cancer review explains how antibody-drug conjugates deliver lethal payloads to tumors, why resistance emerges, and which next-generation ...

A new perspective argues that the Fc glycan of monoclonal antibodies should be treated as an intrinsic design variable, integrating ...

FDA researchers developed ARTEMIS, a framework that distills thousands of monoclonal antibody papers into compact, steerable AI memory that outperforms ...

A new review examines how trogocytosis, the process by which cells nibble membrane fragments from one another, shapes immune regulation, ...

Researchers have developed anti-Gn monoclonal antibodies and a magnetic nanoparticle-enhanced lateral flow assay that detects SFTS virus antigen within 45 ...

A new PLOS Biology study shows that the breadth of ACE2 receptor usage among bat sarbecoviruses predicts both their host ...

Researchers have mapped conserved epitopes on the sarbecovirus spike protein that allow three monoclonal antibodies to neutralize a wide range ...

Computational genomic and structural analyses of Bundibugyo virus sequences from the 2026 outbreak predict that the MBP134 antibody cocktail retains ...

Researchers have developed the first monoclonal antibodies and ELISA capable of detecting the bacterial nuclease toxin USP, a protein linked ...

A new case report documents 127 days of persistent SARS-CoV-2 RNA positivity in a woman with chronic lymphocytic leukaemia, underscoring ...

Penn State researchers found that blocking the protein VPS34 raises levels of the GD2 molecule on neuroblastoma cells, making them ...