Childhood Tuberculosis Advances Hinge on Diagnosis, Care Links, and Prevention
A new editorial argues that progress in pediatric tuberculosis depends less on novel tests than on connecting diagnostics to timely ...
Tag: Molecular diagnostics
Glowing RNA Molecules Light Up Cancer Cells for Precision Oncology
A new review in Molecular Biology Reports surveys how fluorogenic RNA aptamers, engineered RNA strands that switch on fluorescence upon ...
Cloning-Based 16S rDNA PCR Libraries Outperform Culture in Polymicrobial Bloodstream Infections
A new study shows that a cloning-based 16S rDNA PCR library method detects more pathogens than blood culture while maintaining ...
ICU-acquired pneumonia: why detecting a pathogen is not the same as diagnosing disease
A new Perspective argues that ICU-acquired pneumonia should be managed as an explicit attribution problem, grading how plausibly a detected ...
From One Health Surveillance to Mpox and Prions: New Research Tracks the Rise of Emerging Diseases
A new Frontiers research collection examines how emerging and re-emerging diseases, from arboviruses to prions, are tracked through One Health ...
Hidden Lung Threat: Ecuador’s First Six-Year Map of Nontuberculous Mycobacteria
A six-year study at Ecuador's national reference laboratory identified 225 nontuberculous mycobacteria isolates across 11 species, suggesting NTM infections are ...
Rapid PCR Testing Guided by Pharmacists Cuts Antibiotic Overuse in COPD Flare-Ups
A prospective study in North Macedonia found that pharmacist-interpreted multiplex PCR testing enabled antibiotic discontinuation in nearly two-thirds of hospitalized ...
New SCAR Markers Identify Deadly Aspergillus Fungi in Lung Fluid Samples
Mexican researchers have developed three SCAR molecular markers that detect Aspergillus section Fumigati, A. flavus, and A. niger directly in ...
Drug-Resistant Skin Fungus Trichophyton indotineae Spreads Worldwide
A review in Frontiers in Tropical Diseases documents the worldwide spread of the terbinafine-resistant skin fungus Trichophyton indotineae and the ...
High-Risk HPV Genotypes Not Covered by Vaccines Dominate Cervical Infections in Lagos Women
A study of 165 women in Lagos, Nigeria, found that high-risk HPV genotypes not fully covered by current vaccines, led ...
Chromoblastomycosis: A Century-Old Fungal Disease Where Science Outpaces Care
A new synthesis in PLOS Neglected Tropical Diseases shows how molecular advances in chromoblastomycosis have failed to improve diagnosis and ...
Colorimetric LAMP Test Spots Hidden Malaria Infections in the Peruvian Amazon
A colorimetric LAMP assay combined with column-based DNA extraction markedly outperformed microscopy for detecting low-density Plasmodium vivax and P. falciparum ...
Hidden Malaria Duo: First Evidence of Delayed Dual Plasmodium Infection in an Ivorian Patient
A case report in BMC Infectious Diseases describes the first evidence of a Plasmodium falciparum–Plasmodium ovale co-infection in an Ivorian ...
Hidden Scourge: Genital Tuberculosis Strikes Young Women and Evades Diagnosis
A five-year Chinese hospital study of 5,123 women with tuberculosis shows that genital tuberculosis overwhelmingly strikes women in their twenties, ...
PCR Test Comparison Reveals Hidden Burden of Cattle Anaplasmosis in Venezuela
A new PCR-based study in Venezuela shows that msp5-targeting diagnostics outperform msp2 primers for detecting Anaplasma marginale and reveals a ...
Sequencing Showdown: Two DNA Tests Match Up in the Race to Diagnose Tuberculosis
A propensity score-matched study of 403 patients finds targeted and metagenomic next-generation sequencing statistically equivalent for diagnosing pulmonary tuberculosis, though ...
Rapid Sputum Test Proves Highly Accurate for Detecting Tuberculosis in High-Risk Children
A six-year South African study found that the Xpert MTB/RIF Ultra test on induced sputum achieved over 90 percent sensitivity ...
Molecular screening finds no trace of dangerous mycobacteria in Algerian milk
A molecular survey of 391 milk samples from farms in northern Algeria detected no DNA from five pathogenic mycobacterial species, ...
Syphilis Bacteria Found in Spinal Fluid Across All Disease Stages
A new study finds Treponema pallidum DNA in the cerebrospinal fluid of HIV-negative patients at every stage of syphilis, including ...
Rapid PCR Test Delivers Joint Infection Answers in Hours Instead of Weeks
A rapid PCR-based molecular test on sonication fluid from revised joint implants delivered results within hours and showed high clinically ...
