RNA-processing enzyme Star-PAP stabilizes insulin receptor mRNA and guards fat tissue
A rare Star-PAP variant found in lean individuals led researchers to discover that this polyadenylation enzyme stabilizes insulin receptor mRNA ...
Tag: metabolic homeostasis
Metabolic Homeostasis and Women’s Reproductive Health: A Bidirectional Dialogue
A new Nature Metabolism review proposes an integrated framework in which bidirectional crosstalk between metabolic organs and endocrine mediators governs ...
Scientists Discover the Built-In Brake That Keeps a Cancer-Drug Plant From Poisoning Itself
Researchers have identified a self-limiting CrJAZ1-CrVQ4/9-CrWRKY4 transcriptional circuit in the Madagascar periwinkle that acts as both accelerator and brake on ...
MOTS-c: The Tiny Mitochondrial Peptide That Behaves Differently in Health and Cancer
A new review argues that the mitochondrial peptide MOTS-c acts as a context-dependent stress signal with protective roles in metabolic ...
Gut Microbes Track the Hidden Toll of Mountain Hypoxia and Recovery
A large multi-omics study finds that high-altitude hypoxia and reoxygenation leave month-long redox and metabolic stress signatures, with gut microbes ...
Glutamate Deficit Affects Mouse Reproduction, Metabolism Sex-Specifically
In a groundbreaking study published in Biology of Sex Differences, researchers have unveiled a pivotal discovery regarding the role of ...
