Targeting gut dysbiosis: a new frontier in MASLD management
Metabolic dysfunction-associated steatotic liver disease, known as MASLD, has quietly become the most common chronic liver condition on the planet, ...
Tag: MASLD
Edible Potentilla longifolia Shows Preventive Power Against Fatty Liver Disease
An edible Inner Mongolian vegetable, Potentilla longifolia, prevented high-fat diet-induced fatty liver disease by activating AMPK and suppressing NF-κB/MAPK pathways, ...
Simple Blood-Based Scores Outperform Ultrasound Expectations in Spotting Fatty Liver Among Diabetes Patients
A Sri Lankan study of 260 newly diagnosed type 2 diabetes patients found that the Fatty Liver Index and Hepatic ...
A Racing Heart May Signal Metabolic Trouble in Turner Syndrome, Case Report Suggests
A case report of an 18-year-old woman with Turner syndrome proposes that persistent sinus tachycardia may serve as an accessible ...
Low Vitamin D Tracks With Liver Scarring in Fatty Liver Disease, But Causality Remains Unclear
A new cross-sectional study of 301 patients in Dubai found that vitamin D deficiency is highly prevalent in MASLD and ...
Japan’s Five-Decade Hepatitis Campaign Reshapes the Nation’s Liver Cancer Burden
A Hiroshima University review published in The Lancet Regional Health - Western Pacific shows that nearly five decades of national ...
Simple Blood and Body Metrics Predict Fatty Liver Disease in Older Adults
Chinese researchers developed an interpretable logistic regression model that identifies metabolic dysfunction-associated steatotic liver disease in middle-aged and older adults ...
Fat Rewrites the Rules of Liver Cancer Across Every Disease Stage
A new review proposes that lipid metabolism plays fundamentally different roles at each stage of fatty liver disease progression to ...
Air Pollution’s Fingerprint in the Blood Reveals How Fine Particles May Drive Fatty Liver Disease
A UK Biobank study of over 52,000 adults identifies a 700-protein blood signature that statistically mediates the link between fine ...
Fatty Liver Disease Affects One in Five Children Worldwide, Landmark Scan Study Finds
An international study of more than 9,300 children across 17 countries finds that fatty liver disease affects about one in ...
Rare Sugar D-Allulose Eases Fatty Liver Damage in Diabetic Mice by Reshaping Gut Microbes and Tryptophan Signaling
A new mouse study shows the rare sugar D-allulose reduces fatty liver and inflammatory injury in type 2 diabetes while ...
When Heart, Liver and Metabolism Collide: A Deadly Syndemic That Cuts Years Off Life
A study of nearly 470,000 adults in the UK and US finds that the co-occurrence of cardiovascular disease, fatty liver ...
The Liver Keeps Its Own Clock: Late-Night Meals Linked to Fatty Liver Disease and Cirrhosis
A large analysis of nearly 200,000 health professionals found that people who reported eating late at night had a 20 ...
AI and Digital Health Set to Reshape Cardiometabolic Medicine, Major Review Finds
A comprehensive BMC Medicine review finds that artificial intelligence and digital health tools show strong potential to transform cardiometabolic care, ...
Blood Sugar Control, Not Weight Loss, Reversed Liver Fibrosis Risk in Diabetic Patients
A 24-week clinical trial in patients with type 2 diabetes and fatty liver disease found that optimal glycemic control, but ...
Gut microbes and T cells drive chronic liver disease through a two-way immune dialogue
A new review maps how gut microbes and their metabolites bidirectionally shape T cell immunity to drive autoimmune, alcohol-associated, metabolic ...
Anti-Inflammatory, Antioxidant-Rich Diets Linked to Longer Survival in Fatty Liver Disease
A large NHANES-based study finds that pro-inflammatory diets roughly double mortality risk in fatty liver disease while antioxidant-rich diets are ...
Fatty Liver Cells Turn On a Caspase-2 Death Pathway That Damps Hepatitis B Replication
New in vitro research shows that free fatty acid–induced steatosis activates a TNF-α/TNFR1–Caspase−8/Caspase−2 apoptotic pathway that is associated with reduced ...
Single-cell atlas of human liver pinpoints scar macrophages as drug target for fibrosis
A 649,295-cell single-cell atlas of human livers has revealed a pro-inflammatory OLR1-positive scar-associated macrophage population that expands across chronic liver ...
How Stressed Blood Flow and Metabolism Drive Ageing Arteries
A new review proposes that disturbed blood flow and metabolic stress converge to drive endothelial cell senescence, amplifying cardiometabolic vascular ...
