Tag: Liquid Biopsy

A new review maps four molecular routes by which CRISPR systems can detect cancer-linked DNA methylation in cell-free DNA, and ...

A comprehensive review maps why liquid biopsy tests for early cancer detection struggle to translate from promising studies into approved ...

A gold nanoparticle-decorated MBene thin-film transistor array detected salivary microRNA-27a down to 3.2 femtomolar and distinguished a small preliminary cohort ...

A case report in Oncotarget describes how an international molecular tumor board weighed treatment options for a 52-year-old woman with ...

A nearly 1,800-patient international observational study found that the investigational PANXEON blood test detected 87% of stage 1 and 2 ...

A prospective observational study linked circulating tumor DNA fraction and copy-number burden with progression and survival in 78 patients receiving ...

The 35,878-person PATHFINDER 2 trial found 6.5-fold more cancers when Galleri was added to routine screening, but it did not ...

A prospective study found that a multicancer blood test detected signals across 17 cancer types with 99.64% specificity, but randomized ...

A University of Michigan study of two independent cohorts found that patients with lobular metastatic breast cancer are far more ...

A new method called ReadsRatio estimates tissue contributions to circulating cell-free DNA from unmethylated read ratios in cell type-specific marker ...

A landmark Viewpoint argues that the gap between ctDNA's prognostic power and clinical utility reflects misalignment of biology, timing, assay ...

A systematic review of 89 studies identifies 53 microRNAs regulating neuroblastoma cell differentiation, with miR-124, miR-34, and miR-506-3p promoting maturation ...

A new methods article outlines how artificial intelligence should be used to integrate liquid biopsy biomarkers in cancer research, finding ...

A 69-microRNA signature measured in blood exosomes classified Parkinson's disease with an AUC of 0.952 across cohorts, while multi-omics analyses ...

Researchers combined high-purity vesicle proteomics, computational gene expression analysis and optimized immuno-isolation to validate NRXN3 as a candidate marker for ...

A patient-specific whole-genome liquid biopsy detected lung cancer DNA associated with recurrence months before tumors became visible on imaging in ...

A 2026 review finds that GSTP1 promoter methylation is a powerful prostate-cancer signal with limited routine clinical use because its ...

A proposed liquid-biopsy strategy combines tumor-associated and organ-associated markers on circulating extracellular vesicles to infer metastatic sites, but it remains ...

A retrospective analysis of 1,101 serum samples used explainable artificial intelligence to prioritize circulating microRNAs that distinguished pancreatic cancer from ...

A 2026 review found encouraging diagnostic results for DNA methylation biomarkers in ovarian cancer but concluded that prospective evidence at ...