Telomerase Inhibition: New Cancer Therapies and Clinical Trials
A review in Biological Research details how telomerase-targeted therapies, including imetelstat and peptide vaccines, are advancing cancer treatment by disrupting ...
Tag: Kinase Inhibitors
Small trials, big approvals: FDA data reveal how companion diagnostics reshaped cancer drug development
A survey of 87 FDA-approved cancer drugs linked to companion diagnostic assays found that most were cleared on the basis ...
Four Decades of Anticancer Quinazoline Research Mapped in New Bibliometric Study
A new bibliometric and pharmacological review of 423 Scopus-indexed publications maps four decades of anticancer quinazoline research, revealing a 2018 ...
Edited book reviews heterocyclic approaches in anticancer drug research
An edited multidisciplinary volume reviews heterocyclic scaffolds, evaluation methods, emerging drug-design approaches and translational challenges in anticancer research.
Oxadiazole compound shows potent selectivity against oligodendroglioma cells
Researchers have synthesized a series of 1,3,4-oxadiazole derivatives and evaluated their anticancer potential against HS683 human oligodendroglioma cells, identifying one ...
Purine Scaffold Powers a New Generation of Drug Candidates Across Cancer and Infectious Disease
A comprehensive review maps how strategic chemical modifications to the purine scaffold yield potent drug candidates against cancer, malaria, drug-resistant ...
MLK Regulates Tumor Growth and Blood Vessel Formation
In the realm of cancer research, a pivotal study has shed light on the role of mixed lineage kinase (MLK) ...
