AI Reads Bladder Cancer Slides and Pinpoints RTN3 Behind Chemotherapy Resistance
A multimodal AI model built from routine pathology slides predicts bladder cancer survival and led researchers to RTN3, which drives ...
A multimodal AI model built from routine pathology slides predicts bladder cancer survival and led researchers to RTN3, which drives ...
CRISPR-engineered cervical cancer cells carrying the PIK3CA-E545K mutation show coordinated immune signaling and metabolic rewiring, driven by suppressed lipid biosynthesis ...
A new study maps how the fungal pathogen Nakaseomyces glabratus uses three specialized sugar kinases, trehalose-6-phosphate feedback, gene expression tuning ...
A study of 724 STEMI patients found that elevated glucose, lactate, pyruvate and citrate were each significantly associated with death ...
A new study finds that CD14-positive monocytes from rheumatoid arthritis and psoriatic arthritis patients show distinct inflammatory, metabolic, epigenetic and ...
A retrospective study of 1,979 patients finds that clear cell renal cell carcinoma diagnosed at age 45 or younger shows ...
Scientists studying zebrafish have identified a previously underappreciated immune checkpoint that appears to represent an ancient forerunner of the mammalian ...
A new review proposes an immunometabolic framework for paediatric refractory Mycoplasma pneumoniae pneumonia, while stressing that most supporting evidence remains ...
An integrative analysis of bulk and single-cell transcriptomic data identifies ENO1 as a reproducibly upregulated metabolic factor associated with CD4+ ...
A multi-omics Mendelian randomization study identifies HKDC1 and ITGAM as suggestive glycolytic candidates genetically associated with insulin resistance in metabolically ...
Lab-grown blood-brain barrier cells from adults with ADHD carrying PARK2 copy number variations show small genotype-linked changes, while culture duration ...
A new study links the metabolic enzyme ECHS1 to hypoxia-responsive PGK1 crotonylation and malignant phenotypes in prostate cancer cell and ...
A new study shows that TGF-β-driven PFKM downregulation reroutes glucose toward glycogen storage and promotes invasive, mesenchymal-like behavior in lung ...
A long noncoding RNA called CYP4A22-AS1 promotes radioresistance in cervical adenocarcinoma by shuttling YBX1 into the nucleus to activate the ...
Laboratory experiments with human tonsil-derived fibroblasts show that senescent lymphoid stromal cells suppress B cell proliferation through contact-dependent mechanisms despite ...
An integrated multi-omics study of rice seed germination reveals a three-phase carbon metabolism program, from β-amylase-driven starch hydrolysis to sucrose ...
Integrated transcriptomic and cell-line analyses link GSTK1 expression to favorable gastric cancer prognosis and to IL-6/JAK2/STAT3 signaling, glycolysis-related proteins, and ...
A cell and patient-cohort study links hypoxia-induced GP73 to HIF-1α-dependent glycolysis, growth, invasion and markers of transarterial chemoembolization resistance in ...
A multi-omics culture study found that 100 micromolar indole-3-lactic acid promoted Lemna aequinoctialis growth and altered metabolites, lipids, gene expression, ...
A 2026 review maps altered glucose, lipid and amino-acid metabolism across four major lung cell populations and identifies promising but ...
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